Clinical Trials Logo
  1. Home
  2. Dupuytren's Disease
  3. NCT01226121

Safety and Efficacy of Delayed Manipulation After Xiaflex Treatment in Subjects With Dupuytren's Contracture

Dupuytren's Disease Clinical Trial

Official title:
A Post Market, Open-Label Study of the Safety and Efficacy of Delayed Manipulation After Xiaflex Treatment in Subjects With Dupuytren's Contracture

Clinical Trial Summary

The purpose of this study is to determine if of manipulation of digits following collagenase injection for treatment of Dupuytren's contracture is effected by the amount of time between injection and manipulation.

Clinical Trial Description

Patients with Metacarpophalangeal joint contractures caused by Dupuytren's disease will be evaluated as to the timing of the finger manipulation procedure that is performed following collagenase injection. Three groups will be evaluated: group 1 will have the manipulation procedure on the day following collagenase injection, group 2 will have the manipulation procedure on the second day following collagenase injection,and group 3 will have the manipulation procedure on the fourth day following collagenase injection, ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01226121
Study type Interventional
Source Indiana Hand to Shoulder Center
Contact
Status Terminated
Phase Phase 4
Start date December 2010
Completion date December 2012
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05300893 - Effectiveness of Night Splinting After Percutaneous Needle Fasciotomy in Dupuytren's Contracture N/A
Recruiting NCT04122313 - Post-contracture Release Radiation for Dupuytren's Disease
Completed NCT01498640 - Retreatment of Recurrent Dupuytren's Contractures Phase 4
Completed NCT01450397 - MRI Results in Dupuytren's Contracture Before and After Injection With Xiaflex Phase 4
Completed NCT03180957 - Repurposing Anti-TNF for Treating Dupuytren's Disease Phase 2
Completed NCT00575458 - Splinting for Dupuytren's Contracture Release N/A
Completed NCT00260429 - Collagenase in the Treatment of Dupuytrens Disease Phase 3
Recruiting NCT05067764 - Efficacy of Aponeurectomy on the 2-year Recurrence Rate of Dupuytren's Disease N/A
Completed NCT02725528 - Evaluation of Xiaflex: Trial of Effectivenss iN Dupuytren's Phase 3
Completed NCT02193828 - Phase 2a Dose-Ranging Study to Evaluate Safety and Effectiveness of AA4500 in Treatment of Dupuytren's Disease Nodules Phase 2
Completed NCT00954746 - Longterm Observational Study in Subjects Treated With AA4500 in AUX-CC-854, 856, 857, 858 & 859 N/A
Completed NCT04874870 - Effectiveness of Splinting After Collagenase Injection Phase 3
Recruiting NCT06263699 - Goniometry and Goniometric Measurement on Standardised Images in Dupuytren's Disease
Not yet recruiting NCT02294890 - Knee Stiffness in Fibrosis Diathesis N/A
Completed NCT04669704 - Effectiveness of a Tele-Rehabilitation Evidence-based Tablet App for Rehabilitation in Traumatic Bone and Soft Injuries of the Hand, Wrist and Fingers. N/A
Recruiting NCT05440240 - Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture Phase 4
Active, not recruiting NCT01446432 - Validation of Two New Questionnaires for Dupuytren's Disease N/A
Recruiting NCT06281509 - Palmaris Longus Muscle and Dupuytren N/A
Recruiting NCT06321991 - Nodular Shrinking in Dupuytren Disease Phase 2
Not yet recruiting NCT06142929 - Micronerves in Dupuytren and the Impact of Its Dissection on Recurrence