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Ductal Breast Carcinoma in Situ clinical trials

View clinical trials related to Ductal Breast Carcinoma in Situ.

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NCT ID: NCT05318274 Recruiting - Clinical trials for Invasive Breast Cancer

Hypofractionated Radiation Therapy vs Standard Treatment in Breast Cancer.

Start date: April 26, 2021
Phase: N/A
Study type: Interventional

An explanatory study comparing complementary treatment to breast conservative surgery with radiation therapy DCIS, T1-T2 N0 M0 (AJCC v8) 1 week schedule vs 3.1 weeks standard schedule, in order to determine the equivalence of local tumor control, survival, acute and chronic toxicity. Shorter curse of radiation therapy may lead to similar local control of tumor cells and lower rates of toxicity than 3.1 standard treatment.

NCT ID: NCT04537312 Active, not recruiting - Clinical trials for Anatomic Stage II Breast Cancer AJCC v8

Prospective Pilot Study of Robot-assisted Nipple Sparing Mastectomy (RNSM)

Start date: November 17, 2020
Phase: N/A
Study type: Interventional

This is a pilot study to determine safety, efficacy, and potential risks of robot assisted nipple sparing mastectomy (RNSM), by utilizing the daVinci surgical system.

NCT ID: NCT04009044 Recruiting - Cancer Survivor Clinical Trials

Topical Afimoxifene in Treating Patients With Breast Cancer Who Have Undergone Radiation Therapy on One Breast

Start date: February 17, 2020
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well topical afimoxifene works in treating patients with breast cancer who have undergone radiation therapy on one breast. Topical afimoxifene is a quick-drying medicated gel that may block the growth of breast cancer cells when applied to the breast skin. The purpose of this research is to determine what effect, if any, differences in skin type between women have on the delivery of topical afimoxifene to the breast tissue, and whether radiation affects the delivery of topical afimoxifene to breast tissue.

NCT ID: NCT03909282 Recruiting - Clinical trials for Ductal Breast Carcinoma in Situ

Surgical Excision vs Neoadjuvant Radiotherapy+Delayed Surgical Excision of Ductal Carcinoma

NORDIS
Start date: March 22, 2019
Phase: N/A
Study type: Interventional

The purpose of this pilot study is to compare by pathological findings surgical excision versus neoadjuvant radiotherapy followed by delayed surgical excision of ductal carcinoma in situ (DCIS)

NCT ID: NCT03546972 Active, not recruiting - Obesity Clinical Trials

Diabetes Prevention Program With or Without Hunger Training in Helping to Lower Breast Cancer Risk in Obese Participants

Start date: December 17, 2017
Phase: N/A
Study type: Interventional

This pilot trial studies how well a diabetes prevention program with or without hunger training works in helping to lower breast cancer risk in obese participants. A diabetes prevention program involves learning about and receiving materials on different strategies to encourage weight loss, and hunger training involves learning how to recognize hunger. It is not yet known whether adding hunger training to a diabetes prevention program helps participants control their weight that could reduce the risk of some cancers.

NCT ID: NCT03391388 Active, not recruiting - Clinical trials for Estrogen Receptor Positive

3D-CRT, Proton, or Brachytherapy APBI in Treating Patients With Invasive and Non-invasive Breast Cancer

Start date: June 16, 2015
Phase: Phase 2
Study type: Interventional

This phase II trial studies the side effects of three-dimensional conformal external-beam photon radiotherapy (3D-CRT), proton, or brachytherapy accelerated partial breast irradiation (APBI) in treating patients with breast cancer that has or hasn't spread from where it began in the breast to surrounding normal tissue. Radiation therapy such as photon and proton partial breast external beam radiotherapy, uses high energy x-rays to kill tumor cells and shrink tumors. Giving radiation therapy in different ways may kill more tumor cells. Brachytherapy, also known as internal radiation therapy, uses radioactive material placed directly into or near a tumor to kill tumor cells. It is not yet known whether photon or proton partial breast external beam radiotherapy or partial breast brachytherapy works better in treating patients with breast cancer.

NCT ID: NCT03345420 Active, not recruiting - Clinical trials for Stage II Breast Cancer

Hypofractionated Radiation Therapy in Treating Patients With Stage 0-IIB Breast Cancer

NOVEMBER
Start date: December 12, 2017
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well hypofractionated radiation therapy works in treating patients with stage 0-IIB breast cancer. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects.

NCT ID: NCT03077841 Active, not recruiting - Clinical trials for Invasive Breast Carcinoma

Hypofractionated Partial Breast Irradiation in Treating Patients With Early Stage Breast Cancer

Start date: March 6, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

This phase II trial studies how well hypofractionated partial breast irradiation works in treating patients with early stage breast cancer. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects. Treating only the part of the breast where the cancer started may lead to fewer side effects than standard treatment.

NCT ID: NCT02993159 Recruiting - Clinical trials for Estrogen Receptor Positive

Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through the Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast

Start date: May 31, 2017
Phase: Phase 2
Study type: Interventional

This randomized phase IIB trial studies how well tamoxifen or afimoxifene works in treating patients with estrogen receptor positive breast cancer. Estrogen can cause the growth of breast cancer cells. Hormone therapy using tamoxifen citrate or afimoxifene may fight breast cancer by blocking the use of estrogen by the tumor cells.

NCT ID: NCT02961790 Completed - Breast Carcinoma Clinical Trials

Oxybutynin Chloride in Managing Hot Flashes

Start date: December 9, 2016
Phase: Phase 3
Study type: Interventional

This randomized phase III trial studies how well oxybutynin chloride works in managing hot flashes in patients who are not candidates for, or not interested in hormone replacement therapy. Previous studies have shown that oxybutynin is effective in managing hot flashes, however doses used in prior studies have resulted in side effects. This trial is evaluating lower doses of oxybutynin with the goal of determining if they are efficacious with less side effects. ADAM-VTE