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Dry Eye clinical trials

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NCT ID: NCT04838223 Enrolling by invitation - Dry Eye Clinical Trials

Neurosensory Abnormalities in SymptomAtic Ocular Surface Patients (NASA)

NASA
Start date: July 2, 2021
Phase:
Study type: Observational

This study is designed to measure how common nerve abnormalities are within a group of patients who feel discomfort within their eyes.

NCT ID: NCT04837807 Completed - Dry Eye Clinical Trials

Digital Device Users Who Are Treated With Systane Hydration PF

Start date: August 18, 2021
Phase: Phase 4
Study type: Interventional

Systane Hydration PF is a recently released preservative-free artificial tear that is able to supplement the ocular surface's moisture while simultaneously soothing the eye. While Systane Hydration PF should in theory improve the symptoms and subsequently the quality of life of patients who have DES, this clinical application has yet to be tested. This drop furthermore is available in both unit-dose and multi-dose options; however, it is unclear if patient perceive a difference between the two dispensing methods. Therefore, the primary purpose of this study is to recruit patients who have DES and to treat them with Systane Hydration PF and determine how regular use of this drop impacts a patient's ocular surface symptoms and overall quality of life. This study will secondarily compare the two dispensing methods to determine if patients prefer one method over the other.

NCT ID: NCT04835623 Completed - Dry Eye Clinical Trials

CEQUA for Sjogren's Syndrome Dry Eye

Start date: June 21, 2021
Phase: Phase 4
Study type: Interventional

The primary objective of this study is to show that CEQUA (cyclosporine 0.09% ophthalmic solution) improves symptoms of dry eye disease in a population of patients with Sjogren's Syndrome diagnosis.

NCT ID: NCT04830956 Completed - Dry Eye Clinical Trials

Evaluation of Comfort in Subjects With Moderate Dry Eye Disease

Start date: June 30, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the comfort of an ocular lubricant in dry eye subjects. This study will be conducted in Canada and Australia.

NCT ID: NCT04817085 Completed - Dry Eye Clinical Trials

An Evaluation of the Clinical Utility and Safety of the Visant Medical Canalicular Plug

Start date: October 6, 2020
Phase: N/A
Study type: Interventional

This study is designed to evaluate the clinical utility and safety of the Visant Medical Canalicular Plug compared to a commercially available canalicular plug.

NCT ID: NCT04803240 Completed - Dry Eye Clinical Trials

Survey: Evaluation of Ocular Surface Disease Symptoms and Patient Satisfaction With Thealoz® Duo After 84 Days of Daily Treatment

Start date: April 1, 2019
Phase:
Study type: Observational

Multi-centre, international, non-interventional, prospective survey

NCT ID: NCT04795752 Active, not recruiting - Dry Eye Clinical Trials

Prospective, Randomized, Masked, Controlled Trial To Evaluate The Safety And Effectiveness Of The TearCare® System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease (SAHARA)

Start date: April 23, 2021
Phase: N/A
Study type: Interventional

To demonstrate the safety and effectiveness of TearCare® procedures compared to Restasis® to treat the signs and symptoms of dry eye disease in adult patients.

NCT ID: NCT04789824 Completed - Dry Eye Clinical Trials

The Impact of Eyelid Hygiene on Ocular Surface

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

Dry eye is one of the most common eye diseases and it is known to be an ever-increasing public health problem in risky groups. Physical conditions (heat, light, humidity,ventilation), anesthetic gases, chemical-containing disinfectants and antiseptics are risk factors for dry eyes in operating rooms. In addition, the fact that surgery is a job that requires constant attention is considered among the factors that increase the risk of dry eye as it reduces the number of blinking. In the literature review, eye hygiene (hot application, massage, cleaning) is recommended as an application that protects and improves eye health. Because it has been reported to have significant positive effects on eye fatigue, dry eye symptoms and vision in both healthy and dry eyes. However, "daily eye hygiene" is a little-known practice in almost every society. In this context, the effect of eye hygiene on ocular surface moistening and vision-related quality of life in operating room workers was investigated in this study.The research was conducted as a randomized controlled experimental study between May 2018 and May 2019. All participants working in the operating room and meeting the inclusion criteria were included in the study. The group in which the participants will be included was determined by simple randomization. Eye hygiene training was given to the intervention group and eye hygiene practice was followed for 12 weeks. The control group was not intervened. Tear film stability and vision-related quality of life scores of both groups before and after 12 weeks of training were compared.

NCT ID: NCT04785261 Recruiting - Dry Eye Clinical Trials

Effect of Traditional Chinese Medicine on Basic Tear Secretion and Tear Cytokines in Patients With Dry Eye Disease

Start date: March 16, 2021
Phase: Phase 2
Study type: Interventional

This is a single center, randomized, single-blind, controlled pilot study of CJDHW plus JWXYS as a complementary therapy to treat dry eye disease during a 12-week period. The investigators intend to enroll 60 subjects aged between 20 and 75 years old (treatment group(N=30); controlled group(N=30)). Treatment group will be treated with artificial tears combined with TCM, while control group will use artificial tears only. The aim of this study is to explore the efficacy of TCM for dry eye disease.

NCT ID: NCT04747977 Completed - Dry Eye Clinical Trials

To Assess the Efficacy and Safety of OTX-DED for the Short-term Treatment of Signs and Symptoms of Dry Eye Disease

Start date: February 12, 2021
Phase: Phase 2
Study type: Interventional

To assess the efficacy and safety of OTX-DED for the short-term treatment of signs and symptoms of dry eye disease.