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Dry Eye clinical trials

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NCT ID: NCT05027087 Completed - Dry Eye Clinical Trials

The Effect of a Novel Blueberry Supplement on Dry Eye Disease

PLUM
Start date: September 9, 2021
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate the efficacy of a novel oral supplement (gummy bear) with blueberry powder on reducing dry eye signs and symptoms and assess its safety.

NCT ID: NCT05011708 Completed - Dry Eye Clinical Trials

I-DROP MGD Symptomatic Relief and Tear Film Stability

Start date: August 23, 2021
Phase: N/A
Study type: Interventional

The objective of the study is to compare the difference in tear film stability and symptomatic relief between I-DROP MGD and another commercially available drop in the Canadian market.

NCT ID: NCT04971031 Completed - Dry Eye Clinical Trials

A Clinical Trial to Assess Subjects With Dry Eye Disease.

Start date: June 15, 2021
Phase: Phase 2
Study type: Interventional

A Multi-Center Randomized, Double-Masked, Parallel Design, Vehicle-Controlled Phase 2 Clinical Trial to Assess the Efficacy and Safety of 0.25% Reproxalap Ophthalmic Solution Compared to Vehicle in Subjects with Dry Eye Disease

NCT ID: NCT04960696 Completed - Dry Eye Clinical Trials

Effect on Ocular Surface Symptoms of Online Education

Start date: April 14, 2021
Phase:
Study type: Observational [Patient Registry]

retrospective, observational study.

NCT ID: NCT04952987 Recruiting - Dry Eye Clinical Trials

Dry Eye Management With 3% Diquafosol Before and After Cataract Surgery

Start date: January 1, 2021
Phase:
Study type: Observational

The objective of this study is to evaluate the efficacy of Diquafosol 3% in the management of dry eyes before and after cataract surgery. Patients with pre-existing dry eyes and planned for cataract surgery will be started on Diquafosol eyedrops prior to surgery and treatment will be continued after cataract surgery. Eligible patients will undergo evaluation of dry eye at baseline and subsequently started on treatment with Diquafosol for the duration of 4 weeks before surgery. Further evaluations will be conducted on the day of surgery and at designated time points during and up to 12 weeks after surgery.

NCT ID: NCT04949295 Completed - Dry Eye Clinical Trials

Evaluation of Ocular Surface in Hemodialysis Patients by Ocular Surface Analyzer

Start date: January 1, 2021
Phase:
Study type: Observational

We clinically observed that some hemodialysis patients had corneal epithelial dryness, shedding, edema, and persistent epithelial nonunion after ocular surgery, which seriously affected the effect of surgery, and it is necessary to study the ocular surface characteristics of hemodialysis patients. In this study, we examined the ocular surface and analyzed and investigated the characteristics of the ocular surface in hemodialysis patients to provide a basis for ocular surface intervention or treatment in hemodialysis patients before ocular surgery in clinical practice.

NCT ID: NCT04911361 Completed - Dry Eye Clinical Trials

The DEPOT Study (Dry Eye Prescription Options for Therapy)

Start date: August 10, 2021
Phase: Phase 4
Study type: Interventional

Assessing DEXTENZA efficacy and safety when placed within the lower eyelid canaliculus for dry eye flares in comparison to topical loteprednol suspension.

NCT ID: NCT04899518 Completed - Dry Eye Clinical Trials

ALY688 Ophthalmic Solution in Subjects With Dry Eye Disease

OASIS-1
Start date: May 19, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

Study Evaluating the Safety and Efficacy of Two Concentrations (0.4% and 1%) of ALY688 Ophthalmic Solution in Subjects with Dry Eye Disease

NCT ID: NCT04889950 Completed - Dry Eye Clinical Trials

Clinical Study to Evaluate the Safety and Effectiveness of The Tixel Fractional System in the Treatment of Meibomian Gland Disfunction

Start date: October 26, 2021
Phase: N/A
Study type: Interventional

A Randomized, Masked (Evaluator), Controlled, Prospective Pilot Study of the Effectiveness and Safety of the Tixel®, Versus LipiFlow® in the Treatment of Meibomian Gland Dysfunction. Up to 30 patients (60 eyes) to be randomized in up to 2 clinical sites in Israel and/or Europe. study subject will receive three (3) treatments with Tixel in a monthly interval, and a single treatment for the control group. Follow-up will occur 1 month and 3 months following the last treatment.

NCT ID: NCT04877210 Recruiting - Dry Eye Clinical Trials

Effects of Topical Insulin on Levels of Tear Inflammatory Mediators

Start date: October 22, 2020
Phase: Phase 1
Study type: Interventional

60 samples are take to determine the effects of topical insulin on tear inflammatory mediators interleukin 1a, interleukin 6 and matrix metalloprotenase 9 in diabetics with dry eye disease.