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Dry Eye Syndromes clinical trials

View clinical trials related to Dry Eye Syndromes.

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NCT ID: NCT05536661 Completed - Evaporative Dry Eye Clinical Trials

Impact of Tear Substitute Use on Dry Eye in Gamers.

HYAGAME
Start date: July 4, 2019
Phase: N/A
Study type: Interventional

Clinical, prospective, comparative, controlled, single-blind study, on the signs and symptoms of dry eye before and after 3 days of playing video games with the use of artificial tears (Hyabak) versus no intervention.

NCT ID: NCT05528016 Completed - Dry Eye Clinical Trials

Short and Long-term Results of Skin Versus Skin Plus Orbicularis Resection Blepharoplasty

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

This study aims to evaluate the short and long-term effects of skin-only and skin+muscle excision blepharoplasty on corneal nerves, dry eye parameters, meibomian glands, and eyebrow position.

NCT ID: NCT05523531 Completed - Dry Eye Clinical Trials

Prospective Single-center Long-term Follow-up Study of a Series of Cases Previously Included in the QUALVIDON Study

QUALVIDON2
Start date: September 15, 2022
Phase:
Study type: Observational

Dry eye affects millions of people around the world. Some dry eye patients complain of neuropathic eye pain that can affect their quality of life. From August 2016 to June 2017, the QUALVIDON study (NCT03296111), conducted at the Adolphe de Rothschild Foundation Hospital, assessed pain and its impact on quality of life using self-administered questionnaires in a series of dry eye patients. This 2nd study, entitled QUALVIDON2, focuses on the outcome of patients previously included in QUALVIDON.

NCT ID: NCT05515471 Completed - Clinical trials for Treatment of Dry Eye Disease With Meibomian Gland Dysfunction

Effect of SHR8058 on Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction

Start date: February 4, 2021
Phase: Phase 3
Study type: Interventional

The study is being conducted to evaluate the efficacy and safety of SHR8058 eye drops for patients with dry eye disease.

NCT ID: NCT05505292 Completed - Dry Eye Clinical Trials

Lifitegrast 5% for the Treatment of Dry Eye In Habitual Soft Contact Lens Wearers

Start date: September 22, 2022
Phase: Phase 4
Study type: Interventional

This is a prospective, single site, randomized, double masked, comparator-controlled study designed to evaluate the efficacy of lifitegrast ophthalmic solution 5% in treating the symptoms of dry eye in soft contact lens wearers as compared to control. We hypothesize that there will be a significant improvement in dry eye symptoms in contact lens wearers using lifitegrast as compared to those being treated with control (lifitegrast vehicle).

NCT ID: NCT05497479 Completed - Dry Eye Disease Clinical Trials

Study Evaluating Techniques for Measuring Tear Production

MTP
Start date: December 9, 2021
Phase: Phase 1
Study type: Interventional

This will be a vehicle-controlled, masked, randomized study conducted at a single site in the United States. All participants enrolled will have Dry Eye Disease (DED). The study will consist of 2 Visits. At Visit 1, eligibility will be assessed at Screening. All eligible subjects will then be enrolled and randomized to one of two treatment groups (1:1): active (0.003% AR-15512) or control (AR-15512 vehicle). Subjects in each treatment group will then be randomized 1:1 to which Visit (Visit 1 or 2) anesthetic will be used with the Schirmer test.

NCT ID: NCT05493111 Completed - Dry Eye Disease Clinical Trials

A Long-Term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512

COMET-4
Start date: November 1, 2022
Phase: Phase 3
Study type: Interventional

This will be a 12-month, multicenter, vehicle-controlled, double-masked, randomized Phase 3 study conducted at approximately 10 sites in the United States. All subjects enrolled will have dry eye disease (DED). The study will consist of a Baseline (Day 1) visit as well as visits at Day 14, Day 90, Day 180, Day 270, and Day 365 (Study Exit).

NCT ID: NCT05487547 Completed - Dry Eye Disease Clinical Trials

Feasibility of IPL Combined With RF for Treatment of DED Due to MGD

Start date: July 21, 2022
Phase: N/A
Study type: Interventional

The purpose of this single-arm pilot study is to evaluate the feasibility and safety of combination therapy of intense pulsed light (IPL) and (Radiofrequency) RF for treatment of Dry eye disease (DED) due to Meibomian gland dysfunction (MGD).

NCT ID: NCT05486728 Completed - Dry Eye Disease Clinical Trials

Phase II Study of SHJ002 Sterile Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease

Start date: February 8, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this study is to measure efficacy and safety with SHJ002 sterile ophthalmic solution compared to vehicle in participants with Dry Eye Disease (DED). SHJ002 is an antisense oligonucleotide to neutralize a specific microRNA.

NCT ID: NCT05481450 Completed - Dry Eye Clinical Trials

Efficacy and Safety Safety of Nutritears® in Adults With Dry Eye Syndrome

Start date: August 15, 2022
Phase: N/A
Study type: Interventional

This is a prospective, randomized, double-blind, parallel, placebo-controlled, clinical interventional study. The purpose of this study is to evaluate the efficacy and safety of Nutritears®, a dietary supplement of OmniActive Health Technologies, in adult subjects with dry eye syndrome (DES). Subjects shall be instructed to consume one capsule of their assigned investigational study product every morning after the breakfast, at the same time every day, for 56 days (8 weeks).