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Dry Eye Syndromes clinical trials

View clinical trials related to Dry Eye Syndromes.

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NCT ID: NCT03318874 Completed - Dry Eye Syndromes Clinical Trials

Optimization of the Treatment of Dry Eye Disease Caused by Meibomian Gland Dysfunction

Start date: October 19, 2017
Phase: Phase 4
Study type: Interventional

An open label, randomized controlled study in a Norwegian population with meibomian gland dysfunction. Patients will be randomized to one of two groups: THERA°PEARL Eye Mask (Bausch & Lomb Inc., New York, USA) or Blephasteam® (Spectrum Thea Pharmaceuticals LTD, Macclesfield, UK). All patients will receive Hylo-comod (URSAPHARM Arzneimittel GmbH, Saarbrücken, Germany).

NCT ID: NCT03302273 Completed - Dry Eye Clinical Trials

Corneal Epithelial Stem Cells and Dry Eye Disease

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

To study of a novel, therapeutic Human Cells, Tissues, and Cellular and Tissue-Based Product (HCT/P) in the treatment of severe dry eye disease that is failing conventional treatments. This pilot study will carefully observe and monitor each qualifying and willing individual for response to treatment, signs of toxicity and adverse effects from the treatment, and for ability of the treatment to improve comfort and restore vision.

NCT ID: NCT03292809 Completed - Dry Eye Disease Clinical Trials

CyclASol for the Treatment of Signs and Symptoms of Dry Eye Disease (DED)

Start date: October 19, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

The objective of this study is to assess the efficacy, safety, and tolerability of CyclASol Ophthalmic Solution in comparison to vehicle for the treatment of the signs and symptoms of DED.

NCT ID: NCT03287635 Completed - Dry Eye Disease Clinical Trials

Clinical Efficacy of H.P. Acthar Gel 80 U/ml to Improve the Signs and Symptoms in Subjects With Dry Eye Disease

Start date: July 1, 2018
Phase: Phase 4
Study type: Interventional

Study Title: A Phase 4 Study to Assess the Clinical Efficacy of H.P. Acthar Gel 80 U/ml to Improve the Signs and Symptoms in Subjects with Dry Eye Disease

NCT ID: NCT03265652 Completed - Dry Eye Clinical Trials

IPL and MGX Versus MGX Alone in the Treatment of Dry Eye Disease Secondary to MGD

Start date: May 15, 2018
Phase: N/A
Study type: Interventional

The aim of the current study is to examine the contribution of intense pulsed light (IPL) for relieving signs and symptoms of dry eye due to meibomian gland dysfunction. The effect of IPL will be examined in a study designed as a randomized controlled trial. In the study arm, subjects will undergo 4 treatment sessions, consisting of IPL pulses immediately followed by expression of the meibomian glands. In the control arm, subjects will undergo the same treatments, except that the IPL pulses will be disabled. For each subject, the duration of the study will be 10 weeks, as explained in the detailed description,

NCT ID: NCT03265327 Completed - Dry Eye Clinical Trials

Effect of an Oral Supplement Containing Omega-3 and Omega-6 on Dry Eye Symptoms

TURMERIC
Start date: August 16, 2017
Phase: N/A
Study type: Interventional

This study will investigate the effectiveness of two oral supplements on the ocular signs and symptoms in symptomatic dry eye patients. Eligible participants will be given one of two oral supplements to take once a day for up to three months.

NCT ID: NCT03237936 Completed - Keratitis Clinical Trials

Effect of IKERVIS® Eye Drops Once Daily on the Quality of Vision in Dry Eye Disease Patients With Severe Keratitis

FAST
Start date: March 28, 2017
Phase: Phase 4
Study type: Interventional

The proposed 3-month study is a prospective, open-label, multicentre, phase IV, proof of concept study. The study is designed to assess the effect on the quality of vision of IKERVIS® (1mg/mL ciclosporin) eye drops administered once daily in dry eye disease (DED) patients with severe keratitis, as well as its safety and efficacy.

NCT ID: NCT03228784 Completed - Clinical trials for Incidence and Severity of Dry Eye After Myopic LASIK

The Effect of Ablation Depth on Dry Eye After LASIK Treatment of Myopia

Start date: June 1, 2013
Phase: N/A
Study type: Interventional

The study tried to find the relation between ablation depth and degree of dryness after LASIK treatment of myopic patients

NCT ID: NCT03226769 Completed - Dry Eye Syndromes Clinical Trials

Safety and Efficacy of TrueTear™ for the Treatment of Meibomian Gland Disease

Start date: July 26, 2017
Phase: N/A
Study type: Interventional

This study will compare the safety and efficacy of TrueTear™ to standardized moist heat compress (Thermalon® Dry Eye Compress) for the treatment of Meibomian Gland Disease (MGD).

NCT ID: NCT03226444 Completed - Dry Eye Clinical Trials

Lacripep™ in Subjects With Dry Eye Associated With Primary Sjögren's Syndrome

Start date: June 30, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

The objective of this study is to evaluate the efficacy and safety of two strengths of Lacripep™ ophthalmic solution versus placebo administered three times daily for four weeks in subjects with a diagnosis of Dry Eye associated with documented Primary Sjögren's Syndrome