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Dry Eye Syndromes clinical trials

View clinical trials related to Dry Eye Syndromes.

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NCT ID: NCT04837807 Completed - Dry Eye Clinical Trials

Digital Device Users Who Are Treated With Systane Hydration PF

Start date: August 18, 2021
Phase: Phase 4
Study type: Interventional

Systane Hydration PF is a recently released preservative-free artificial tear that is able to supplement the ocular surface's moisture while simultaneously soothing the eye. While Systane Hydration PF should in theory improve the symptoms and subsequently the quality of life of patients who have DES, this clinical application has yet to be tested. This drop furthermore is available in both unit-dose and multi-dose options; however, it is unclear if patient perceive a difference between the two dispensing methods. Therefore, the primary purpose of this study is to recruit patients who have DES and to treat them with Systane Hydration PF and determine how regular use of this drop impacts a patient's ocular surface symptoms and overall quality of life. This study will secondarily compare the two dispensing methods to determine if patients prefer one method over the other.

NCT ID: NCT04835623 Completed - Dry Eye Clinical Trials

CEQUA for Sjogren's Syndrome Dry Eye

Start date: June 21, 2021
Phase: Phase 4
Study type: Interventional

The primary objective of this study is to show that CEQUA (cyclosporine 0.09% ophthalmic solution) improves symptoms of dry eye disease in a population of patients with Sjogren's Syndrome diagnosis.

NCT ID: NCT04831177 Completed - Clinical trials for Myopic LASIK Candidates With Spherical Equivalent up to - 10 Diopters

Thin-Flap Laser in Situ Keratomileusis Associated Dry Eye

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

Laser in situ keratomileusis (LASIK) eye surgery continues to be the most common refractive procedure used to correct different forms of ametropia. Although the introduction of femtosecond technology has markedly reduced the incidence of intraoperative flap complications and allowed a better control on flap parameters, dry eye remains one of the most challenging postoperative complications.

NCT ID: NCT04830956 Completed - Dry Eye Clinical Trials

Evaluation of Comfort in Subjects With Moderate Dry Eye Disease

Start date: June 30, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the comfort of an ocular lubricant in dry eye subjects. This study will be conducted in Canada and Australia.

NCT ID: NCT04819269 Completed - Dry Eye Disease Clinical Trials

Tivanisiran for Dry Eye in Subjects With Sjögren's Syndrome

Start date: May 25, 2021
Phase: Phase 3
Study type: Interventional

This study will examine the efficacy and safety of tivanisiran sodium eye drops versus vehicle after a 2-week run-in phase when dosed once daily for 3 months in subjects with signs and symptoms of dry eye disease (DED) due to Sjögren's Syndrome.

NCT ID: NCT04817085 Completed - Dry Eye Clinical Trials

An Evaluation of the Clinical Utility and Safety of the Visant Medical Canalicular Plug

Start date: October 6, 2020
Phase: N/A
Study type: Interventional

This study is designed to evaluate the clinical utility and safety of the Visant Medical Canalicular Plug compared to a commercially available canalicular plug.

NCT ID: NCT04806256 Recruiting - Dry Eye Syndromes Clinical Trials

CDSS of Traditional Chinese Medicine Intervention for Dry Eye Syndrome

Start date: July 11, 2020
Phase: N/A
Study type: Interventional

This project is based on artificial intelligence (AI) algorithms to screen the effective methods of traditional Chinese medicine intervention for dry eye and its applicable conditions, and optimize the traditional Chinese medicine intervention plan for dry eye through the evaluation of evidence-based medicine and expert consensus, and construct the Clinical Decision support system of traditional Chinese medicine intervention for dry eye, secondly, a real-world prospective cohort study design is adopted, the CDSS system is used in the ophthalmology clinic, and its practical application effect on patients with dry eye is evaluated.

NCT ID: NCT04795752 Active, not recruiting - Dry Eye Clinical Trials

Prospective, Randomized, Masked, Controlled Trial To Evaluate The Safety And Effectiveness Of The TearCare® System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease (SAHARA)

Start date: April 23, 2021
Phase: N/A
Study type: Interventional

To demonstrate the safety and effectiveness of TearCare® procedures compared to Restasis® to treat the signs and symptoms of dry eye disease in adult patients.

NCT ID: NCT04792580 Recruiting - Clinical trials for Graft-versus-host-disease

The Effects and Safety of 5% Lifitegrast Ophthalmic Solution in Subjects With Dry Eye Disease in Ocular Graft-versus-Host Disease

Start date: October 22, 2022
Phase: Early Phase 1
Study type: Interventional

The objective of this study is to evaluate the clinical efficacy of 5% lifitegrast ophthalmic solution in subjects with dry eye disease secondary to ocular Graft-versus-Host Disease compared to placebo.

NCT ID: NCT04785261 Recruiting - Dry Eye Clinical Trials

Effect of Traditional Chinese Medicine on Basic Tear Secretion and Tear Cytokines in Patients With Dry Eye Disease

Start date: March 16, 2021
Phase: Phase 2
Study type: Interventional

This is a single center, randomized, single-blind, controlled pilot study of CJDHW plus JWXYS as a complementary therapy to treat dry eye disease during a 12-week period. The investigators intend to enroll 60 subjects aged between 20 and 75 years old (treatment group(N=30); controlled group(N=30)). Treatment group will be treated with artificial tears combined with TCM, while control group will use artificial tears only. The aim of this study is to explore the efficacy of TCM for dry eye disease.