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Dry Eye Syndromes clinical trials

View clinical trials related to Dry Eye Syndromes.

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NCT ID: NCT05310422 Completed - Dry Eye Disease Clinical Trials

Safety Study of Tivanisiran to Treat Dry Eye

FYDES
Start date: March 24, 2022
Phase: Phase 3
Study type: Interventional

This study will examine the safety of tivanisiran sodium eye drops versus vehicle when dosed once daily for 1 year in subjects with signs and symptoms of dry eye disease (DED).

NCT ID: NCT05306561 Recruiting - Dry Eye Clinical Trials

Evaluating Impact of Systane iLux on Dryness Symptoms and Wearing Time in Contact Lens Users

Start date: January 26, 2022
Phase: N/A
Study type: Interventional

To evaluate dry eye symptoms and contact lens wearing times after a single iLux treatment by evaluating change from baseline in OSDI scores, subjective CLDEQ8 and CL wearing time questionnaires, and meibomian gland secretion scores.

NCT ID: NCT05304650 Recruiting - Dry Eye Syndromes Clinical Trials

A Usability Study of External Neuromodulation With iTEAR100 Generation 2

Start date: March 1, 2022
Phase: Phase 4
Study type: Interventional

A Usability Study of External Neuromodulation With iTEAR100 Generation 2. A study which evaluates user ability to train and access the iTEAR100 device in a telehealth environment.

NCT ID: NCT05304637 Recruiting - Dry Eye Clinical Trials

Usability, Immediate, and 30 Day Effect of External Neuromodulation With iTEAR100 Generation 2 in Dry Eye Patients

Start date: March 1, 2022
Phase: Phase 4
Study type: Interventional

iTEAR generation 2 will be supplied t eligible subjects at Day 0. At Day 30, symptom questionnaires and ophthalmic exam will be performed.

NCT ID: NCT05299619 Completed - Dry Eye Clinical Trials

Tixel Treatment for Dry Eye Symptoms

Start date: March 28, 2019
Phase: N/A
Study type: Interventional

Dry eye syndrome is caused by a chronic lack of sufficient lubrication and moisture on the surface of the eye. Consequences of dry eyes range from subtle but constant eye irritation to significant inflammation and even scarring of the front surface of the eye. Meibomian Gland Dysfunction (MGD) refers to the condition where the glands are not secreting enough oil or when the oil they secrete is of poor quality. Tixel is a fractional skin rejuvenation system, which relies on direct thermal energy delivery, free of any radiation type such as laser, RF, etc. The energy is transferred via a continuously sterile, thermal titanium element (the "Tip"), located on the applicator (the "Handpiece"). In this study, the principal investigator will undertake standard treatment of periorbital wrinkles with Tixel and observe the effect on dry eye disease symptoms and signs.

NCT ID: NCT05292755 Completed - Dry Eye Syndromes Clinical Trials

Effects of Carboxymethylcellulose Artificial Tears on the Eye Microbiome

Start date: April 22, 2022
Phase: Phase 4
Study type: Interventional

Carboxymethylcellulose (CMC), a common component in artificial tears, has been shown to modify the gut microbiome. The study is examining its effects on the eye microbiome, which may have implications on ocular disease and artificial tear choice. The study will administer artificial tears containing CMC to the treatment group and artificial tears without CMC to the control group. Surveys and conjunctival swabs will be collected before and after treatment for bacterial genome sequencing and analyzed by R statistical packages.

NCT ID: NCT05288582 Completed - Dry Eye Clinical Trials

Tear Lipid Layer Thickness Assessments With Perfluorohexyloctane Eye Drops

Start date: March 27, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to explore the tear lipid layer quantitatively and qualitatively before and after use of a perflurohexyloctane eye drop (NovaTears)

NCT ID: NCT05285644 Completed - Dry Eye Disease Clinical Trials

Study Evaluating the Safety and Efficacy of AR-15512

COMET-2
Start date: May 9, 2022
Phase: Phase 3
Study type: Interventional

This will be a Phase 3, multicenter, vehicle-controlled, double-masked, randomized study conducted at approximately 20 sites in the United States. All subjects enrolled will have dry eye disease (DED). The study will consist of Screening (Day -14) and Baseline (Day 1) visits as well as visits at Day 7, Day 14, Day 28, and Day 90 (Study Exit).

NCT ID: NCT05271422 Completed - Dry Eye Disease Clinical Trials

Application of Pulse Electrical Stimulation Around Eye in Dry Eye Disease Patients Scheduled for LASEK Surgery

Start date: February 28, 2020
Phase: N/A
Study type: Interventional

This study aims to evaluate the efficacy and safety of applying pulse electrical stimulation around eye in dry eye disease patients who are scheduled for LASEK surgery.

NCT ID: NCT05248698 Recruiting - Dry Eye Clinical Trials

Dry Eye Response to Interval Exercise and Mediterranean Diet

Start date: January 5, 2022
Phase: N/A
Study type: Interventional

in the recent times, dry eye was found to be correlated sedentary life style, obesity, hypertension. So, changing the sedentary lifestyle is recommended