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Dry Eye Syndromes clinical trials

View clinical trials related to Dry Eye Syndromes.

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NCT ID: NCT05745064 Completed - Dry Eye Disease Clinical Trials

A Study of TL-925 as a Treatment for Dry Eye Disease

Start date: February 27, 2023
Phase: Phase 2
Study type: Interventional

In this prospective, Phase 2, multicenter, randomized, double-masked, placebo-controlled, parallel-arm study, approximately 100 subjects with moderate to severe dry eye disease (DED) will be randomly assigned (1:1) to receive either TL-925 or placebo as topical ophthalmic eye drops administered bilaterally BID. The study will comprise two phases: 2-weeks screening/run-in and 4-weeks double-masked treatment.

NCT ID: NCT05743764 Completed - Dry Eye Disease Clinical Trials

HU007 in Patients With Dry Eye Syndrome

Start date: March 23, 2023
Phase: Phase 3
Study type: Interventional

A multicenter, Randomized, Double blind, Restasis®-controlled Non-inferiority, Moisview® Eye Drops Controlled Superiority, Phase III Study to Evaluate the Efficacy and Safety of HU007 Eye Drops in Patients with Dry Eye Syndrome

NCT ID: NCT05741398 Recruiting - Dry Eye Syndromes Clinical Trials

Evaluation of Optical System in the Treatment of - Dry Eye Disease

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Single-center, Prospective, Open Label, with Before-After Study Design, to evaluate the safety and efficacy of the optical system in the treatment of dry eye disease.

NCT ID: NCT05741216 Completed - Dry Eye Clinical Trials

Evaluation of Comfort of Ocular Lubricants in Symptomatic Contact Lens Wearers

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the ocular comfort of 3 ocular lubricants and a comparator.

NCT ID: NCT05738629 Not yet recruiting - Dry Eye Disease Clinical Trials

Safety and Efficacy of Pluripotent Stem Cell-derived Mesenchymal Stem Cell Exosome (PSC-MSC-Exo) Eye Drops Treatment for Dry Eye Diseases Post Refractive Surgery and Associated With Blepharospasm

Start date: March 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the preliminary safety and effectiveness of Pluripotent Stem Cell-derived Mesenchymal Stem Cell Exosome (PSC-MSC-Exo) Eye Drops in the treatment of dry eye diseases post refractive surgery and associated with blepharospasm

NCT ID: NCT05737108 Recruiting - Dry Eye Clinical Trials

Bilberry-containing Capsules for Dry Eye Mitigation

Start date: August 24, 2022
Phase: N/A
Study type: Interventional

This study investigates whether the oral intake of a bilberry capsule product may relieve dry eye symptoms. Participants will be aged between 20 - 65 years of age, with confirmed diagnosis of dry eye status. The participants will be assessed for several parameters and asked to take 4 bilberry capsules per day for 30 days. The parameters will include ocular surface health, tear volume, tear quality, intraocular pressure, and tear compositions. After the 30 days are completed, the participants will be assessed again for the same parameters.

NCT ID: NCT05733624 Completed - Dry Eye Syndromes Clinical Trials

Clinical Trial to Evaluate the Safety and Efficacy of SCAI-001 Compared to Restasis

Start date: January 5, 2023
Phase: Phase 2
Study type: Interventional

This study is planned to Evaluate the Efficacy and Safety of SCAI-001 Eye Drops(Cyclosporine 0.01%, 0.02%) compared to Restasis(Cyclosporine 0.05%) in Patients with Dry Eye Disease.

NCT ID: NCT05724056 Not yet recruiting - Dry Eye Disease Clinical Trials

Idroflog® for Treatment of Dry Eye Disease (IDROFLOG)

IDROFLOG
Start date: March 1, 2023
Phase: N/A
Study type: Interventional

This study aims at demonstrating the non-inferiority of Idroflog compared to sodium hyaluronate 0.18% for the disease improvement of people with documented history of dry eyes and use of tear substitutes for at least 3 months.

NCT ID: NCT05723770 Completed - Clinical trials for Dry Eye Disease (DED)

Effects of NOV03 on the Tear Film

Start date: August 14, 2023
Phase: Phase 4
Study type: Interventional

Determine the effect of a single instillation of NOV03 on the thickness and evaporation rate of the mucus-aqueous layer of the tear film

NCT ID: NCT05720754 Not yet recruiting - Dry Eye Clinical Trials

Temperature on Evaporative Dry Eye

Start date: April 2, 2023
Phase: N/A
Study type: Interventional

Ocular surface temperature of a normal person is around 34.6 degree centigrade. After instilling the eye drop, depending on the temperature of the eye drop and the ocular surface, the ocular surface temperature will temporally increase or decrease sightly. Warm feeling will make blood vessels dilated and more blood will pass through to bring more blood flow out of our body to the heated area of the body and makes cells more permeable. Therefore, heating the ocular surface with heated eye mask after instilling artificial tears has the possibility to improve drug permeability on the ocular surface.