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Dry Eye Syndromes clinical trials

View clinical trials related to Dry Eye Syndromes.

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NCT ID: NCT05056155 Completed - Dry Eye Disease Clinical Trials

Systane Complete Multi-symptom Relief

Start date: November 9, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to demonstrate effective symptom relief with the use of Systane Complete among subjects with dry eye disease (DED).

NCT ID: NCT05042960 Completed - Dry Eye Syndromes Clinical Trials

Computer Screen Properties Study

Start date: September 15, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to identify how various popular methods of changing computer screen settings affect dry eye symptoms (eye pain, grittiness, tearing, burning, etc.). Specifically, this study will examine if there are differences in effects of blue light blocking (F.lux app or night shift) versus reducing screen brightness on the symptoms of dry eye.

NCT ID: NCT05031806 Completed - Dry Eye Disease Clinical Trials

Evaluation of the Safety, Tolerability and Efficacy of iNexin™ for the Treatment of the Signs and Symptoms Associated With Dry Eye Disease

Start date: September 28, 2021
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to evaluate the safety and tolerability of iNexin™ The secondary objective is to compare the efficacy of iNexin™ to Vehicle for the treatment of the signs and symptoms associated with dry eye disease.

NCT ID: NCT05027087 Completed - Dry Eye Clinical Trials

The Effect of a Novel Blueberry Supplement on Dry Eye Disease

PLUM
Start date: September 9, 2021
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate the efficacy of a novel oral supplement (gummy bear) with blueberry powder on reducing dry eye signs and symptoms and assess its safety.

NCT ID: NCT05017870 Completed - Dry Eye Syndromes Clinical Trials

[KSR-001-P01]Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristic of KSR-001

Start date: December 2, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and pharmacokinetic characteristic of KSR-001.

NCT ID: NCT05017844 Completed - Dry Eye Syndromes Clinical Trials

[KSR-001-P02] Phase 2b/3 Study, Evaluate the Efficacy and Safety of KSR-001 in Patients With Dry Eye Syndrome

Start date: February 18, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of KSR-001 in patients with Dry Eye Syndrome

NCT ID: NCT05011708 Completed - Dry Eye Clinical Trials

I-DROP MGD Symptomatic Relief and Tear Film Stability

Start date: August 23, 2021
Phase: N/A
Study type: Interventional

The objective of the study is to compare the difference in tear film stability and symptomatic relief between I-DROP MGD and another commercially available drop in the Canadian market.

NCT ID: NCT05003128 Completed - Dry Eye Disease Clinical Trials

Changes in Tear Lipid Layer Thickness After Short Exposure to Light Emitting Diode Displays

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

Video display terminals (VDTs) are ubiquitous, and engagement in digital screens has grown substantially across all age groups worldwide. Prolonged exposure to VDTs is associated with the development of various health problems. By now, it is unclear whether transient exposure to VDTs leads to ocular surface changes, especially regarding lipid layer thickness (LLT). This study aim to determine if short-term exposure to light-emitting diodes (LEDs) leads to ocular parameter changes. This is a prospective, cross-sectional study. Patients were recruited at the National Cheng-Kung University Hospital, a tertiary referral center in southern Taiwan, for examination, including best-corrected visual acuity (BCVA), intraocular pressure (IOP), lipid layer thickness (LLT), and blink rates and patterns before and after watching an LED display for 15 minutes. The estimated result is that the LLT and blink rates will decrease after VDT watching.

NCT ID: NCT05002036 Completed - Dry Eye Syndromes Clinical Trials

Management of Dry Eye Disease After Cataract Surgery With Topical Hyaluronic Acid and Gingko Biloba

Start date: February 1, 2021
Phase: Phase 4
Study type: Interventional

Cataract surgery is one of the main causes of Dry Eye Disease (DED). This paper aimed at evaluating the prevalence of iatrogenic DED on a population of patients without DED receiving cataract surgery, and the impact of an eyedrop containing hyaluronic acid and gingko biloba (HA-GB, Trium free eyedrops, Sooft srl, Italy). In this phase-IV trial we enrolled 40 patients with no DED. Patients were seen at baseline, day 1, week 1 and week 4. At each visit patients received Ocular Surface Disease Index (OSDI) questionnaire, Anterior segment ophthalmoscopy with grading of conjunctival hyperemia, fluorescein tear break-up time (TBUT), grading of fluorescein corneal staining (epithelial damage); adherence and tolerability using a visual analogue scale were checked at week 1 and 4. At day 0 patients underwent cataract surgery (2.4 mm temporal incision) and were randomized to standard postoperative care (control group) or standard postoperative care + HA-GB given three times a day for 4 weeks (HA-GB group).

NCT ID: NCT04971031 Completed - Dry Eye Clinical Trials

A Clinical Trial to Assess Subjects With Dry Eye Disease.

Start date: June 15, 2021
Phase: Phase 2
Study type: Interventional

A Multi-Center Randomized, Double-Masked, Parallel Design, Vehicle-Controlled Phase 2 Clinical Trial to Assess the Efficacy and Safety of 0.25% Reproxalap Ophthalmic Solution Compared to Vehicle in Subjects with Dry Eye Disease