Clinical Trials Logo
  1. Home
  2. Drug-resistant Tuberculosis
  3. NCT06224036

Clinical Study of JDB0131 Benzenesulfonate Tablets in Patients With Drug-sensitive Pulmonary Tuberculosis

Drug-resistant Tuberculosis Clinical Trial

Official title:
A Randomized, Open, Multicenter, Phase IIa Clinical Study on the Early Bactericidal Activity, Safety, Tolerance and Pharmacokinetics of JDB0131 Benzenesulfonate Tablets in Drug Sensitive Pulmonary Tuberculosis Patients

Clinical Trial Summary

A randomized, open, drug controlled design of experiments was used to evaluate the early bactericidal activity, safety, tolerance and pharmacokinetic characteristics of JDB0131 benzenesulfonate tablet taken orally by drug sensitive pulmonary tuberculosis patients. Five groups are proposed to be set up in this test (JDB0131 benzenesulfonate 100mg BID, JDB0131 benzenesulfonate 200mg QD, JDB0131 benzenesulfonate 200mg BID, anti tuberculosis drug fixed dose composite dosage QD is determined according to the weight of the study participants, and delamanid 100mg BID)

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06224036
Study type Interventional
Source Beijing Chest Hospital
Contact Naihui Chu, Dr.
Phone +86 13611326573
Email dongchu1994@sina.com
Status Recruiting
Phase Phase 2
Start date October 31, 2023
Completion date March 31, 2024
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05017324 - Sequencing Mycobacteria and Algorithm-determined Resistant Tuberculosis Treatment Trial N/A
Active, not recruiting NCT04179500 - A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis Volunteers Phase 2
Completed NCT02234908 - Rewards for Tuberculosis Contact Screening N/A
Completed NCT02236078 - Brief Bactericidal Activity of Anti-Tuberculosis Drugs Phase 1
Completed NCT04147676 - Evaluation of Centralised TB Assay Solutions
Completed NCT04493671 - Evaluate Safety, Tolerability, PK of TBAJ-876 in Healthy Adults Phase 1
Completed NCT03338621 - Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patients Phase 2/Phase 3
Completed NCT05526911 - A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults Phase 1
Completed NCT03266003 - An Evaluation of Traditional Directly Observed Therapy (DOT) and Electronic DOT for TB Treatment N/A
Not yet recruiting NCT05553236 - Pragmatic Use of Next-generation Sequencing for Management of Drug-resistant Tuberculosis N/A
Completed NCT04119375 - Behavior Change and Digital Health Interventions for Improved TB Treatment Outcomes N/A