Drug-induced Liver Injury Clinical Trial
Official title:
A Multi-center, Prospective, Non-interventional Cohort Study on Drug Induced Liver Injury in Mainland China
This is a multi-center, prospective, non-interventional cohort study .
Its primary objectives are:
1. assess DILI patients' clinical characteristics, disease progression and influencing
factors in clinical practice;
2. learn about suspected drug caused DILI,rechallenging, liver biochemical abnormalities
mode, etc.
The main purpose of this study is to understand patients with DILI clinical outcome and
influencing factors in China's second and tertiary general hospitals (including Western
medicine hospital, Chinese medicine hospital andIntegrated traditional Chinese and Western
Medicine Hospital) and vulnerabilities of drug-induced liver injury specialist hospital
(tuberculosis hospital, Pulmonary, etc.) in mainland.
The main purpose
1. assess the DILI patients' clinical outcomes and influencing factors in the real world;
2. learn about suspected drug caused DILI,rechallenging, liver biochemical abnormalities
mode, etc.
Secondary objectives
1. assess the compliance of the DILI practice to the 2015 vision of the DILI guidelines in
china.;
2. evaluate the histological features of DILI patients;
3. assessment DILI characteristics, prognosis and influencing factors in specific
populations(such as the elderly, children with underlying liver disease background,
etc.)
;
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