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Draining Wound clinical trials

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NCT ID: NCT05311124 Recruiting - Pressure Ulcer Clinical Trials

Direct Application of Integra Bilayer Matrices on Bare Calvarium Without Preliminary Burring

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

This study is to determine if large, full thickness scalp wounds with exposed calvarium resulting from acutely created extirpative defects can be reliably and durably resurfaced with IDRT without burring or fenestration as a preliminary step, regardless of the size of the calvarial defect.

NCT ID: NCT05084378 Active, not recruiting - Clinical trials for Periprosthetic Joint Infection

Evaluation of Emerging New Treatments for Infection Prevention in Total Joint Replacement

PREVENT-IT
Start date: March 11, 2022
Phase: Phase 3
Study type: Interventional

At the end of total joint replacement (TJR) surgery, surgeons wash and clean the surgical wound. This is done to lower the risk of infections. Currently, most surgeons use saline to wash the surgical wound and do not place antibiotics in the wound . However, some recent studies have shown that using povidone-iodine and chlorhexidine-based solutions (both are types of antiseptics) to wash the surgical site and placing antibiotics directly into the wound may be effective in reducing infections in TJR surgery compared to saline and no antibiotics. However, no study has determined which solution is better at reducing the number of infections in patients undergoing TJR. The investigators also do not know if the addition of antibiotics applied to the wound will decrease infections. Currently, there are no surgical guidelines around infection prevention in total joint replacement. A large scale, multi-site, pragmatic 3 x 2 factorial randomized controlled trial is need that compares these six treatment groups. However, before this, a smaller pilot study must be conducted to determine the feasibility of a larger study. PREVENT-iT will address these important gaps in knowledge and clinical practice.

NCT ID: NCT03104153 Completed - Breast Cancer Clinical Trials

Effect of Early Removal of Wound Drains After Mastectomy or Lymph Node Dissection

Start date: September 2015
Phase: N/A
Study type: Interventional

To compare early drain removal versus output-based drain removal, assessing the following end-points: Clinical : risk of seroma and infection, woundhealing, duration of wound care and drain output versus volume of seroma. Quality of life : drain-induced pain, discomfort due to seroma or drain, sleep disturbance and implications on daily activities. Cost-effectiveness