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Clinical Trial Summary

This study is expected to recruit 30 patients with unresectable HCC who will be treated with Donafenib combined with PD-1 + TACE. During the study period, the tumor efficacy and resectability will be evaluated by imaging examination every 6 weeks. Patients with successful transformation can choose hepatectomy or observation. During the study, safety evaluation and effectiveness evaluation will be carried out.


Clinical Trial Description

n/a


Study Design


NCT number NCT05262959
Study type Interventional
Source Shanghai Zhongshan Hospital
Contact Jian Zhou, M.D., Ph.D.
Phone 13801914007
Email Zhou.jian@zs-hospital.sh.cn
Status Recruiting
Phase Phase 2
Start date March 20, 2022
Completion date May 30, 2024