Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03227003
Other study ID # CEID_methylation_1
Secondary ID
Status Completed
Phase N/A
First received July 21, 2017
Last updated July 21, 2017
Start date January 1, 2014
Est. completion date December 31, 2015

Study information

Verified date July 2017
Source Cancer Council Victoria
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The present study used a sub-sample of the Melbourne Collaborative Cohort Study (MCCS) (Milne RL et al, Int J Epidemiol, 2017), who had valid data on dietary intakes (121-item food frequency questionnaire) and valid measures of DNA methylation using the HumanMethylation Infinium 450K Beadchip assay, or using LINE-1, Alu and Sat2 assays.

The investigators studied the association between nutrients involved in one-carbon metabolism and DNA methylation in peripheral blood.


Recruitment information / eligibility

Status Completed
Enrollment 5983
Est. completion date December 31, 2015
Est. primary completion date December 31, 2015
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 27 Years to 80 Years
Eligibility Inclusion Criteria:

- Selected into one of six case-control studies nested in the Melbourne Collaborative Cohort Study

- Completed a 121-item Food Frequency Questionnaire

- Had a blood DNA sample with a measure of methylation

Exclusion Criteria:

- Missing data in any of the outcome, exposure, or confounders (N=797 excluded)

Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Cancer Council Victoria

Outcome

Type Measure Description Time frame Safety issue
Primary Blood DNA methylation Methylation of DNA from peripheral blood, HumanMethylation 450 Beadchip assay 2014-2015
Secondary Blood DNA methylation Methylation of DNA from peripheral blood, LINE-1, Alu, Sat2 2014-2015
See also
  Status Clinical Trial Phase
Completed NCT03642574 - Preimplantation DNA Methylation Test (PIMT) in ART N/A
Completed NCT03787849 - Epigenetics in PostOperative Pediatric Emergence Delirium N/A
Recruiting NCT05442125 - First Live Birth Rate With eSET After Preimplantation Methylome Screening (PIMS) Versus Conventional In-vitro Fertilization N/A
Recruiting NCT05624827 - The Role of FAM19A4 and Hsa-mir-124 Methylation in Predicting Prognosis of Untreated Cervical Intraepithelial Neoplasia 2 (CIN 2) N/A
Completed NCT05085847 - Effects of Mindfulness-based Intervention on Epigenetic Mechanisms, Cognition Function, Stress Response, and Well-being N/A
Recruiting NCT04651946 - Cell-free DNA Methylation for Epithelial Ovarian Cancer Phase 2
Recruiting NCT04646954 - DNA Methylation Testing for the Screening of Uterine Cervical Lesion Phase 3
Recruiting NCT03961191 - DNA Methylation for Screening Uterine Cervical Lesions: A Case-control Study
Not yet recruiting NCT05779904 - Methylation, mIcrobiome, NUtritional sTatus, and dEvelopment of Stunted Children
Recruiting NCT05791149 - Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity N/A
Recruiting NCT05801276 - ctDNA Methylation for Detecting Ovarian Cancer
Recruiting NCT05801263 - ctDNA Methylation for Epithelial Ovarian Cancer
Recruiting NCT05290415 - Host DNA Methylation for Endometrial Cancer Screening
Recruiting NCT05290428 - DNA PAX1 and JAM3 Methylation for Cervical Cancer Screening
Recruiting NCT05290922 - DNA CDO1 and CELF4 Methylation for Endometrial Cancer Screening
Recruiting NCT03960879 - DNA Methylation for Screening Uterine Cervical Lesions
Recruiting NCT05737953 - Construction of Molecular Diagnostic Marker Model for Pancreatic Cystic Tumors Based on Pancreatic Cystic Fluid Samples
Recruiting NCT06140992 - PaCIFiC-CUP Classifies Cancer of Unknown Primary
Completed NCT02032628 - DNA Methylation and Cancer Prevention: Duration and Intensity of Exercise N/A
Completed NCT04568512 - DNA Methylation Biomarker for Diagnosis of Cholangiocarcinoma in Patients With Bile Duct Stricture N/A