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Dizziness clinical trials

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NCT ID: NCT01969513 Completed - Clinical trials for Benign Positional Paroxysmal Vertigo

Effectiveness of the Epley Manoeuvre Performed in Primary Care to Treat Benign Paroxysmal Positional Vertigo

Start date: November 2012
Phase: N/A
Study type: Interventional

Vertigo is a common medical issue with a broad expectrum of diagnoses that requires a global approach to patients through structured clinical interview and physical examination. The main cause of vertigo in primary care is benign paroxysmal positional vertigo (BPPV) that is confirmed by a positive Dix-Hallpike positional test and treated with repositioning manoeuvres. Objective: To evaluate the effectiveness of Epley's manoeuvre performed by general practitioners (GPs) in the treatment of BPPV. Design: randomized clinical trial conducted in primary care. Scope: Two urban centres serving about 50,000 patients. Patients: All patients with newly diagnosed BPPV will be offered to participate in the study and will be randomly assigned to the treatment group (Epley manoeuvre) or control group (sham manoeuvre) and both groups will receive betahistine. Outcome variables will be: response to the Dix Hallpike test, patients will inform if vertigo was present during the last week (dichotomous variable: yes/no), intensity of vertigo symptoms on a Likert scale in the past week, score of Vertigo Handicap Inventory and quantity of betahistine taken. Statistical analysis: Descriptive statistics of all variables collected. Groups will be compared using the intent-to-treat approach and either parametric or nonparametric tests depending on the nature and distribution of the variables. Chi-square test or exact Fisher test will be used to compare qualitative measures and Student's t test o Mann Whitney U test will be used for between-group comparison of variables. Positive results from our study will highlight that treatment of BPPV can be performed by trained GPs and its widespread practice can greatly improve the quality of life of these patients.

NCT ID: NCT01905800 Completed - Clinical trials for Benign Paroxysmal Positional Vertigo

BPPV Treatment in Biaxial Rotational Chair

Start date: August 2013
Phase: N/A
Study type: Interventional

Benign paroxysmal positional vertigo (BPPV) represents the most common cause of labyrinthine vertigo with a lifetime prevalence of 2.4 percent. Onset is most common between the fifth and seventh decades of life. The disease can be a major handicap for the affected patient, and causes a great expense for society. The traditional manual treatment with repositioning maneuvers has greatly improved the possibilities for treatment of BPPV the last decade. However some patients are still difficult to diagnose and treat, and there are some who for health reasons cannot undergo traditional manual treatment. In this perspective there is a demand for a reliable, effective and precise method to treat all semicircular canals for the differentiated patient groups, and the techniques are under continuous development.

NCT ID: NCT01890538 Completed - Peripheral Vertigo Clinical Trials

Comparison of Efficacy Between Piracetam and Dimenhydrinate in Patients With Peripheral Vertigo

Start date: June 2013
Phase: Phase 4
Study type: Interventional

This study aims to investigate efficacy of two different intravenous drugs (dimenhydrinate and piracetam) in the symptomatic management of peripheral vertigo. The patients will be randomized in two groups according to symptomatic treatment modalities: Dimenhydrinate (100 mg) and piracetam (2 g) will be given in 100 cc normal saline in 30 minutes. Each patient will be asked if her/his vertigo symptoms resolved or not, according to a numeric rating scale (0=no vertigo, 10=worst possible vertigo). The patient will be rate the intensity of symptoms in the following times: - Numeric rating scale (1 to 10): Admission - Numeric rating scale (1 to 10): After the study drug (No ambulation)* - Numeric rating scale (1 to 10): After the study drug (Ambulation)* - Ambulation refers to head movements or walking in the room, if applicable.

NCT ID: NCT01827293 Completed - Peripheral Vertigo. Clinical Trials

Promethazine vs. Lorazepam for Treatment of Vertigo

Start date: April 2013
Phase: Phase 3
Study type: Interventional

This study was a prospective, randomized, double-blind, parallel group clinical trial designed to compare the efficacy of intravenous (IV) promethazine and lorazepam for the treatment of peripheral vertigo in Emergency Department setting.

NCT ID: NCT01822002 Recruiting - Clinical trials for Benign Paroxysmal Positional Vertigo (BPPV)

Treatment of Posterior Canal Type of Benign Paroxysmal Positional Vertigo

PC-BPPV
Start date: February 2013
Phase: N/A
Study type: Interventional

To determine the immediate therapeutic efficacies of canalith repositioning maneuvers in each type of BPPV (posterior canal type, apogeotropic horizontal canal type and geotropic horizontal canal type).

NCT ID: NCT01797744 Completed - Stroke Clinical Trials

Vestibular Rehabilitation for Strokepatients With Dizziness

Start date: February 2013
Phase: N/A
Study type: Interventional

Recently, the investigators has shown that dizziness is common among patients with first time stroke and that it affects self perceived health. There are indications that vestibular rehabilitation can have effect of neurological causes of dizziness and vertigo and it therefore seems important to find out if vestibular rehabilitation can affect dizziness among patients with stroke. The aim of this study is to find out if vestibular rehabilitation can have any effect on function, balance and self-rated health among patients with first time stroke.

NCT ID: NCT01759251 Completed - Vertigo Clinical Trials

Effectiveness of Betaserc® (Betahistine Dihydrochloride) in Patients With Vestibular Vertigo in Routine Practice

VIRTUOSO
Start date: January 2013
Phase: N/A
Study type: Observational

The purposes of this international post-marketing observational program is to investigate effectiveness of betahistine dihydrochloride (Betaserc®) tablets and assess the course of vestibular vertigo after treatment discontinuation in population of Russia and Ukraine outpatients suffering from vestibular vertigo in pragmatic clinical settings. Exploratory analyses of results from both participating countries may be expected to provide insights about the subjective circumstances of vestibular vertigo patients in a wider than usual range of gender, underlying ICD-10 diagnosis, national and cultural situations.

NCT ID: NCT01729039 Completed - Dizziness Clinical Trials

Vestibular Rehabilitation and Dizziness

DZO
Start date: November 1, 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether vestibular exercises provide added benefit to balance rehabilitation in older adults with dizziness and normal vestibular function.

NCT ID: NCT01727544 Withdrawn - Clinical trials for Vestibular Dizziness

Vestibular Function Outcome After Cartilage Cap Occlusion Surgery

Start date: August 2012
Phase: Phase 0
Study type: Interventional

The primary objective of this study is to measure objective, functional outcomes of patients undergoing cartilage cap occlusion surgery for a dehiscent superior semicircular canal.

NCT ID: NCT01695577 Completed - Clinical trials for Traumatic Brain Injury

Vestibular Rehabilitation and Balance Training After Traumatic Brain Injury

VRTBI2012
Start date: January 15, 2013
Phase: N/A
Study type: Interventional

The main aim of this study is to evaluate the effect of vestibular rehabilitation and balance training on patients with dizziness and balance problems after traumatic brain injury.