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Distress Respiratory Syndrome clinical trials

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NCT ID: NCT05629793 Not yet recruiting - COVID-19 Clinical Trials

Differential Diagnosis of Persistent COVID-19 by Artificial Intelligence

DICOPERIA
Start date: December 14, 2022
Phase: N/A
Study type: Interventional

The pandemic caused by SARS-CoV-2 infection has resulted, in addition to the well-known acute symptoms, in the emergence of persistent, diffuse and heterogeneous symptoms referred to as persistent COVID. Common symptoms include fatigue, shortness of breath, and cognitive dysfunction, among others, and result in an impact on daily functioning. Symptoms may be new onset, appear after initial recovery from an acute episode of COVID-19, or persist after the initial illness. Cardiac variability (HRV) was initially used in COVID-19 to predict mortality in the acute setting. Dysautonomia which partly evaluates HRV is frequent in patients with persistent COVID. Several groups have used voice or other respiratory noise analysis for the diagnosis of acute COVID. Patients in the persistent COVID cohort will be able to be differentiated from an age, sex and vaccination status matched cohort of recovered COVID patients without sequelae by means of a model created by Machine Learning that will be trained using cardiac variability (HRV), skin conductance and acoustic analysis data. The primary objetive will be to obtain a classification algorithm by Machine Learning to differentiate the group of patients with persistent COVID diagnosis from the paired group of recovered COVID patients without sequelae.

NCT ID: NCT05026645 Enrolling by invitation - Clinical trials for Acute Respiratory Distress Syndrome

The Medical Management in Patients Exposed to Weapons of Mass Destruction

CBRNEObs
Start date: October 1, 2020
Phase:
Study type: Observational

Observation study measuring medical response in contaminated environment.

NCT ID: NCT04745442 Completed - Covid19 Clinical Trials

Pilot Study of Antithrombin as Prophylaxis of Acute Respiratory Distress Syndrome in Patients With COVID-19

Start date: April 27, 2020
Phase: Phase 2
Study type: Interventional

Pilot clinical trial, with a marketed drug -natural component of human plasma-, not approved for this indication, single-center, exploratory, open, randomized, controlled, to study the efficacy and safety of human Antithrombin in patients with confirmed COVID-19 disease and criteria high risk to develop SARS.

NCT ID: NCT04360590 Completed - Weaning Failure Clinical Trials

Pressure Support Ventilation Versus Neurally Adjusted Ventilatory Assist in Difficult to Wean Pediatric Patients

Start date: January 1, 2011
Phase:
Study type: Observational

This study assessed the effects of NAVA versus Pressure Support Ventilation (PSV) on patient-ventilator interaction in pediatric patients with difficult weaning from mechanical ventilation after moderate Pediatric Acute Respiratory Distress Syndrome (PARDS).