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Clinical Trial Summary

For now, neoadjuvant chemoradiotherapy is routinely performed for T3N1-2M0 rectal cancer. However, there are lots of complications following neoadjuvant chemoradiotherapy, such as Wound-related complications, anastomotic leakage, anastomotic stenosis, sexual dysfunction, testicular or ovary failure. Patients undergoing resection for rectal cancer had low rates of local recurrence and long disease-free survival regardless of whether an APR, CAA or low AR was performed. The main purpose of preoperative radiotherapy is to lower the local recurrence. For the T3N1-2M0 rectal cancer with negative circumferential resection margin based on MRI assessment, we suppose might not necessary to receive neoadjuvant chemoradiotherapy, for operation can achieve the negative circumferential resection margin.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03504449
Study type Interventional
Source Beijing Chao Yang Hospital
Contact Jiagang Han, MD
Phone +861085231604
Email wzhj611@163.com
Status Recruiting
Phase N/A
Start date December 1, 2016
Completion date December 1, 2022

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