Gum Acacia and Blood Glucose

Diet Modification Clinical Trial

Official title:

The Effect of Gum Acacia on Satiety, Glycemic Response and Gastrointestinal Tolerance

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03716479
• Other study ID #: STUDY00004203
• Status: Completed
• Phase: N/A
• Start date: October 9, 2018
• Est. completion date: September 1, 2019

Study information

• Verified date: October 2019
• Source: University of Minnesota - Clinical and Translational Science Institute
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study will provide needed insight on the satiety and blood glucose and l effects of the soluble fiber gum acacia at 20g and 40g doses.

Description:

This is a randomized, single-blind, crossover, intervention study testing the satiety and blood glucose effects of the soluble fiber gum acacia.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 48
• Est. completion date: September 1, 2019
• Est. primary completion date: August 31, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria: BMI between 18 and 29 kg/m2

Exclusion Criteria:

• distaste for bagels and cream cheese, orange juice or cheese pizza;

• current smoker;

• restrained eating habits;

• recent weight change;

• any history of disease or significant past medical history;

• are vegetarian;

• do not normally eat breakfast or lunch;

• pregnant or lactating;

• irregular menstrual cycles.

Related Conditions & MeSH terms

• Diet Modification

Intervention

Other:
• Low Fiber
20 g of acacia gum will be added to orange juice
• High Fiber
40 g of acacia gum will be added to orange juice
• Placebo/Control
No acacia gum will be added to orange juice.

Locations

Country	Name	City	State
United States	Department of Food Science and Nutrition	Saint Paul	Minnesota

Sponsors (1)

Lead Sponsor	Collaborator
University of Minnesota - Clinical and Translational Science Institute

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Blood glucose levels	Blood will be taken via finger stick	0, 30, 60, 120, 180, and 240 minutes after breakfast; Area under the curve (AUC) will be calculated for each treatment
Primary	Appetite Sensation	Subjective visual analog scale (VAS) will be utilized to assess hunger, fullness and desire to eat	15, 30, 45, 60, 90, 120, 180 and 240 minutes after breakfast; Area under the curve (AUC) will be calculated for each treatment