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Clinical Trial Summary

Myotonic dystrophy type 1 (DM1) is a neuromuscular disorder in relation with an unstable expansion of CTG repeat. Patients with DM1 are at risk of arrhythmia and conduction disorders. Mortality are mainly related to respiratory failure and sudden death. Patients with DM1 may suffer from obesity, arterial hypertension, diabetes mellitus and sleep apnea. These comorbidities are classically associated with left ventricular diastolic dysfunction (DD) . The investigators aim to assess the prevalence of left ventricular diastolic dysfunction in patients with myotonic dystrophy type 1 , the distribution of DD grading as well as the long-term prognosis of DM1 patients with a left ventricular diastolic dysfunction.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06029192
Study type Observational
Source Centre d'Investigation Clinique et Technologique 805
Contact Abdallah FAYSSOIL, MD PhD
Phone +33147107778
Email abdallah.fayssoil@aphp.fr
Status Recruiting
Phase
Start date June 2, 2023
Completion date November 1, 2023

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