Clinical Trials Logo
  1. Home
  2. Diarrhea
  3. NCT02534272
  4. Details
NCT02534272 Clinical Trial

Study of the Interactions Between Dientamoba Fragilis and the Gut Microbiota

Diarrhea Clinical Trial

Official title:
Study of the Interactions Between Dientamoba Fragilis and the Gut Microbiota

Clinical Trial Details — Status: Terminated

Administrative data
NCT number NCT02534272
Other study ID # 6110
Secondary ID
Status Terminated
Phase
First received
Last updated
Start date February 16, 2016
Est. completion date March 29, 2019

Study information
Verified date August 2021
Source University Hospital, Strasbourg, France
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

D.fragilis is an intestinal protozoon that feeds by phagocytosis of intestinal bacteria. The study aim to determine if the carriage of the intestinal parasite D.fragilis is associated to changes of gut microbiota in subjects presenting with or without intestinal symptoms.

Recruitment information / eligibility
Status Terminated
Enrollment 25
Est. completion date March 29, 2019
Est. primary completion date March 29, 2019
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria for symptomatic group: - male/female aged at least of 18 years - subject with abdominal pain, diarrhea, bloating - no other known intestinal disease Inclusion Criteria for asymptomatic group: - male/female aged at least of 18 years - no known intestinal disease Exclusion Criteria of symptomatic and asymptomatic groups: - chronic intestinal diseases such as IBD, IBS … - intake of antibiotic or probiotic within the 2 last months - subject in exclusion period - subject unable to understand information for a free consent to the study - subject in safeguarding justice or guardianship

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Stool sampling and sequencing of gut microbiota.

Locations
Country Name City State
France Laboratoire de Parasitologie et de Mycologie Médicale du Plateau Technique de Microbiologie des Hôpitaux Universitaires de Strasbourg Strasbourg
France Médecine interne, maladies tropicales et infectieuses Hôpital Civil Strasbourg
France Service d'hépato gastro-entérologie et assistance nutritive Hôpital Hautepierre Strasbourg
France Service de Médecine Interne - Diabète et Maladies métaboliques Hôpital Civil Strasbourg

Sponsors (1)
Lead Sponsor Collaborator
University Hospital, Strasbourg, France

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary 16SrRNA copy numbers Within the 2 days following inclusion
See also
  Status Clinical Trial Phase
Completed NCT06283784 - Study To Evaluate The Efficacy of a Proprietary Mix of Live Probiotics In The Prophylaxis Of Diarrhea In Adult Patients N/A
Recruiting NCT03851835 - Multi-DOSE Oral Ondansetron for Pediatric Acute GastroEnteritis Phase 3
Completed NCT04003181 - The Pathogenesis of Chronic Diarrhoea After Treatment for Cancer in Cecum and the Ascending Colon N/A
Completed NCT03596827 - The Protective Immune Response to Attenuated Enterotoxigenic Escherichia Coli Infection N/A
Recruiting NCT05372068 - Cement flooRs AnD chiLd hEalth (CRADLE) N/A
Completed NCT03972618 - Evaluation of the Efficacy of Sawyer Point One Filters in Schools and Homes in the Dominican Republic N/A
Completed NCT05207618 - Utility of the Administration of Chesnut and Quebracho Extract for Irritable Bowel Syndrome Diarrhea Predominant N/A
Not yet recruiting NCT05052489 - Registry and Clinical Observation of Children With Diarrhoeal Disease
Completed NCT02428647 - Lao Zinc Study: Effects of Two Forms of Daily Preventive Zinc Versus Therapeutic Zinc Supplementation N/A
Completed NCT02541695 - Characterization of Resistance Against Live-attenuated Diarrhoeagenic E. Coli N/A
Completed NCT02197780 - Head-to-head Comparison of Two Fecal Biomarkers to Screen Children for IBD N/A
Completed NCT01739231 - Live Attenuated ETEC Vaccine ACE527 With and Without dmLT Adjuvant in Adults Phase 1/Phase 2
Completed NCT01968408 - Lactobacillus Reuteri DSM 17938 in Preventing Nosocomial Diarrhea in Children Phase 3
Not yet recruiting NCT01382199 - Recombinant Human Lactoferrin Administered Orally for the Prevention of Antibiotic Associated Diarrhea in Adult Patients Phase 3
Terminated NCT01048567 - Efficacy and Safety of Lactobacillus Acidophilus/Rhamnosus Combination for the Prevention of Antibiotic-associated Diarrhea in the Elderly Phase 2
Terminated NCT01472211 - Water-based Zinc Intervention Trial in Zinc Deficient Children Phase 0
Completed NCT01438645 - ScopeGuide-assisted Colonoscopy Versus Conventional Colonoscopy N/A
Completed NCT01371656 - Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation Phase 3
Completed NCT00914225 - Effect of Bednets and a Water Purification Device on HIV Disease Progression Among ART naïve Patients in Kenya N/A
Completed NCT00760851 - Yogurt Study in Children 2-4 Years Old Attending Daycare Phase 3