Diarrhea Clinical Trial
Official title:
Efficacy of Lactobacillus GG With Diosmectite in Treatment Children With Acute Gastroenteritis: A Double Blind Randomized, Placebo- Controlled Trial
Treatment diarrhea with Lactobacillus GG or smectite has proven efficacy. A randomized, double blind, placebo-control trial was performed to assess the effectiveness of both LGG and smectite in management of children with acute gastroenteritis (AGE).
ESPGHAN agreed to use probiotics, with proven efficacy, and smectite in treatment of AGE as
an adjunct to standard rehydration therapy. Among probiotics Lactobacillus GG were found to
be beneficial in meta-analyses. Treatment with LGG was associated with a significant
reduction in diarrhea duration.
A recent review systematically evaluated the efficacy of smectite in treating acute
infections diarrhea in infants and children.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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