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Diagnoses Disease clinical trials

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NCT ID: NCT04480411 Withdrawn - Covid19 Clinical Trials

Use of Technology and Telemedicine to Improve Quality of Care in COVID 19 Patients

Start date: January 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the use of technology including remote vital sign monitoring in improving quality of patient care, decreasing hospital admissions and re-admissions, decreasing hospital length of stay and decreasing use of personal protective equipment.

NCT ID: NCT04401644 Not yet recruiting - Coronavirus Clinical Trials

COVID-19: Laser Interferometry for Rapid Single Coronavirus Detection

COLIDE
Start date: June 2020
Phase: N/A
Study type: Interventional

Using Laser light to detect COVID 19 virus particles in deep throat swab / nasal swab samples.

NCT ID: NCT04388956 Recruiting - Diagnoses Disease Clinical Trials

Thyroid Disease Diagnosis by Mutiple Ultrasonic Factors.

Start date: July 2008
Phase:
Study type: Observational [Patient Registry]

In the outpatient clinic based population setting, the investigators want to reappraise the accuracy of the new model of multi-factorial ultrasound diagnosis with the conventional fine-needle aspiration cytology.

NCT ID: NCT04353141 Recruiting - Pneumonia Clinical Trials

International Lung UltraSound Analysis (ILUSA) Study

ILUSA
Start date: April 28, 2020
Phase:
Study type: Observational

Currently there is a great need for an accurately and rapid assessment of patients suspected for Covid-19. Like CT, Lung Ultrasound (LUS) examination can potentially help with the initial triage of patients but also help track the evolution of the disease. LUS can be used in every setting, including settings with limited infrastructure, allowing the reduction of disparities in trials participation. LUS is also a practical approach that can be used by obstetricians/gynecologists, who are the primary care givers in the labour and delivery room. The International Lung UltraSound Analysis (ILUSA) Study is an international multicenter prospective explorative observational study to assess the predictive value of LUS in Covid-19 suspected and diagnosed pregnant patients.

NCT ID: NCT04334902 Completed - Diagnoses Disease Clinical Trials

Evaluation of Clinical Decision Support System-mPDia for Neurodegenerative Parkinsonism Using MRI Images

Start date: March 13, 2020
Phase:
Study type: Observational

mPDia is a software that has been pre-learned based on a neurodegenerative parkinsonism diagnosis model using Nigrosome 1 MRI images, and clinical decision support system for diagnosing neurodegenerative parkinsonism by automatically analyzing Nigrosome 1 MRI images by assisting the medical team. The specific aims of this study are to evaluate efficacy of mPDia for neurodegenerative Parkinsonism compared to the sensitivity and specificity levels of 18F FP-CIT PET/CT which is currently used to diagnose neurodegenerative parkinsonism.

NCT ID: NCT04322942 Recruiting - Sepsis Clinical Trials

Sepsis Prediction by Monocyte Distribution Width and Procalcitonin

Start date: April 16, 2019
Phase:
Study type: Observational

The mortality rate of sepsis remains as high as 30 to 40%. Early diagnosis and treatment of patients with sepsis reduce mortality significantly. The most commonly used biomarkers in clinical practice are C-reactive protein (CRP) and procalcitonin (PCT). In terms of exploring new diagnostic tools of sepsis, monocyte distribution width (MDW) was first reported in 2017. It was reported as part of the white blood cell (WBC) differential count. MDW greater than 20 and abnormal WBC count together were reported to provide a satisfactory accuracy. The area under curve (AUC) in predicting sepsis-2 is 0.852. It was proposed as a novel diagnostic tool of sepsis in the emergency setting. Nonetheless, the performance of MDW compared with the conventional biomarkers remained unknown. The aim of this study was to compare the diagnostic accuracy of MDW and PCT on sepsis in the emergency department.

NCT ID: NCT04315207 Completed - Lung Cancer Clinical Trials

Breaking Potentially Bad News in Lung Cancer Workup: Telephone Versus In-person Breaking of Final Diagnosis

Start date: October 1, 2012
Phase: N/A
Study type: Interventional

Disclosure of bad news is challenging for patients, relatives and healthcare providers. Current protocols for breaking bad news assume a single, in-person meeting for breaking bad news, however cancer workup is not a single event but a consecutive process with several contacts between patient and physician. Furthermore, an increasing number of patients receive their cancer diagnosis by telephone. The investigators want to examine whether having the result of lung cancer workup by telephone results in worse psychosocial consequences than having the result in-person. Both groups receive information on possibility of cancer at every patient-physician contact.

NCT ID: NCT04311970 Completed - Clinical trials for Eosinophilic Esophagitis

Pilot Study of Esocheck in Eosinophilic Esophagitis

EoE
Start date: August 5, 2020
Phase: N/A
Study type: Interventional

Eosinophilic esophagitis (EoE) is a prevalent chronic inflammatory condition of the esophagus characterized by esophageal eosinophilia that can lead to inflammation and stricture formation. To assess remission, esophagogastroduodenoscopies (EGD) with biopsies are performed. This can lead to multiple EGDs, which are invasive and costly procedures. EsoCheck is a promising noninvasive device. It is an encapsulated balloon that can be easily swallowed and collect cells from the distal esophagus. The primary aim of this study is to determine the feasibility and safety of EsoCheck compared with standard endoscopy and biopsies in the assessment of EoE. This will be a prospective cross-sectional study of adult patients (greater than or equal to 22 years of age) at the University of Pennsylvania with a diagnosis of EoE scheduled for a clinically indicated upper endoscopy.

NCT ID: NCT04299412 Completed - Diagnoses Disease Clinical Trials

Diagnostic Accuracy of the DPP II Assay

Start date: October 28, 2019
Phase:
Study type: Observational

Burkholderia pseudomallei is responsible for melioidosis, a disease that can present a range of signs and symptoms and can be treated by a specific drug regimen. Diagnosis of melioidosis is made by isolation of the bacteria from body fluids or tissues such as blood, skin or sputum. Although this is considered the gold standard, bacterial isolation has low diagnostic sensitivity, requires specific infrastructures (biosafety level 3 laboratories) and skilled staff that are not always available in LMICs. This may lead to inappropriate patient management and care. Chembio, in partnership with FIND, has developed a multiplex lateral flow immunoassay (DPP® Fever Panel II Assay) that is able to detect antigens from common causes of febrile illnesses, included Burkholderia. FIND will conduct a laboratory study in Menzies Health School of Research to estimate the diagnostic accuracy of the DPP II Assay using retrospective samples that are positive for B. pseudomallei. Results will help in estimating the diagnostic accuracy of the assay for this pathogen.

NCT ID: NCT04253509 Completed - Lung Cancer Clinical Trials

Liquid Biopsy Using Methylation Sequencing for Lung Cancer

Start date: February 3, 2020
Phase:
Study type: Observational

This study aims to investigate the utility of circulating tumor DNA (ctDNA) methylation sequencing in the diagnosis of primary lung cancer.