Osteoarthritis, Knee Clinical Trial
Official title:
A Master Protocol for Randomized, Placebo-Controlled, Phase 2 Clinical Trials of Multiple Interventions for the Treatment of Chronic Pain
The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-state addenda (DSA) and intervention-specific appendices (ISAs). The ISAs may start independently of other ISAs as interventions become available for clinical testing.
The chronic pain master protocol (CPMP) establishes entry criteria and includes DSA for osteoarthritis of the knee, chronic low back pain, and diabetic peripheral neuropathic pain. The DSA have specific study elements to appropriately define the target population and unique scales for assessment. Also, the master protocol governs ISAs that may start independently of other ISAs as interventions become available for clinical testing. Note: Results for all outcomes are posted in the intervention records. No need for duplication. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
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N/A | |
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Phase 3 | |
| Completed |
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N/A | |
| Recruiting |
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||
| Completed |
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|
N/A | |
| Active, not recruiting |
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Phase 2 | |
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||
| Recruiting |
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Epidemiology and Nutrition
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| Recruiting |
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Prediction AlgoriThm for regeneraTive Medicine Approach in knEe OA: New Decision-making Process Based on Patient pRofiliNg
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Phase 2 | |
| Not yet recruiting |
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Autologous Adipose Tissue-Derived Mesenchymal Stem Cells (AdMSCs) for Osteoarthritis
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Phase 2 | |
| Not yet recruiting |
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|
N/A | |
| Completed |
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|
N/A | |
| Completed |
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Positive Cueing in Knee Arthroplasty.
|
N/A | |
| Not yet recruiting |
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Phase 4 | |
| Not yet recruiting |
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Topical Tranexamic Acid and Floseal® in Total Knee Arthroplasty
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Phase 4 | |
| Completed |
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|
N/A | |
| Completed |
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The Effect of Medical Exercise Therapy on Pain, Function and Physical Activity in Patients With Knee Osteoarthritis
|
N/A |