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Clinical Trial Summary

The purpose of this study is to evaluate the potential benefits of 145 mg of daily fenofibrate in adults with type 1 diabetes mellitus and pre-existing non-proliferative diabetic retinopathy.


Clinical Trial Description

Diabetes is the most common cause of adult onset blindness. Irreversible vision loss is a most feared complication of diabetes. Fenofibrate is a blood fat lowering drug available in Australia and has been shown to reduce eye damage in people with Type 2 diabetes by 35-40%, and to prevent eye damage in Type 1 diabetic animal models. This study will evaluate the potential benefits of oral Fenofibrate 145mg once daily for average 36 months in 450 adults with Type 1 diabetes mellitus who are at high risk of eye damage. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01320345
Study type Interventional
Source University of Sydney
Contact Liping Li
Phone +61 2 9562 5000
Email fame1eye.study@sydney.edu.au
Status Recruiting
Phase Phase 3
Start date November 3, 2016
Completion date December 2025

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