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Diabetic Foot clinical trials

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NCT ID: NCT06464250 Completed - Diabetic Foot Ulcer Clinical Trials

The Effect of Bundle Approach on Foot Care Behaviors and Diabetic Wound Healing in Patients

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

This study was planned to standardize foot care behaviors with a patient-participated care package approach, to ensure healing of existing wounds, and to evaluate the effect on foot care behaviors to prevent the development of new diabetic foot ulcers. The sample of the study consisted of a total of 97 patients, 49 patients in the care package group and 48 patients in the control group. Hypotheses of the Study H1. The foot care behaviors of patients who receive a patient-participatory care package approach to diabetic foot ulcer prevention will be higher than those of patients who do not receive a care package. H2. Patient-involved care package approach prevents the development of new diabetic foot ulcers. H3. Patient-involved care package approach provides healing of existing diabetic ulcers.

NCT ID: NCT06455475 Not yet recruiting - Diabetic Foot Ulcer Clinical Trials

Derm-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone

Start date: June 2024
Phase: N/A
Study type: Interventional

This randomized controlled study evaluates the adjuvant use of Derm-Maxx in patients with diabetic foot ulcers

NCT ID: NCT06453187 Not yet recruiting - Diabetic Foot Ulcer Clinical Trials

A Modified Platform Trial of Multiple CAMPs for the Management of Diabetic Foot Ulcers and Venous Leg Ulcers

Start date: June 30, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to determine how well multiple CAMPs (Cellular, Acellular and Matrix-Like Products) and Standard of Care work when compared to Standard of Care alone in achieving complete closure of hard-to-heal diabetic foot and venous leg ulcers.

NCT ID: NCT06450015 Completed - Diabetic Foot Clinical Trials

Comparison of Vacuum Assisted Closure and Saline Dressing in Patients With Diabetic Foot Ulcers

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

Conventionally diabetic foot is treated with moist wound dressing and antibiotics but recent studies show that VAC dressing gives better results as compared to conventional saline dressing in treating Diabetic Foot Ulcers. This may decrease amputations rate, work load on hospitals, hospital stay, repeated hospital admissions, unemployment and can improve patient's quality of life. Objective of the study was to compare the effectiveness of Vacuum Assisted Closure therapy with saline dressing in management of diabetic foot ulcers in terms of granulation tissue formation and wound healing.

NCT ID: NCT06449638 Not yet recruiting - Diabetic Foot Clinical Trials

Modified Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of Hard-to-Heal DFUs

CAMPSTIM
Start date: June 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy of four dehydrated complete human placental membrane, also defined as Cellular, Acellular, Matrix-like Products/skin substitutes, plus SOC versus SOC alone in achieving complete closure of hard-to-heal diabetic foot ulcers over 12 weeks using a modified platform trial design.

NCT ID: NCT06444906 Not yet recruiting - Diabetic Foot Ulcer Clinical Trials

A Two-Part, Randomized Study of Dermacyte® Amniotic Wound Care Matrix

Start date: September 1, 2024
Phase: N/A
Study type: Interventional

This is a multi-center, prospective, two-part, controlled study to determine the percentage of participants with complete ulcer closure of a target DFU at Week 12 following treatment with Dermacyte Matrix or SOC.

NCT ID: NCT06442865 Completed - Diabetic Foot Clinical Trials

AMNIODERM+ Medical Device Clinical Study

AMNIODERM+
Start date: November 16, 2022
Phase:
Study type: Observational

This is retrospectively-prospective clinical trial with medical device AMNIODERM+ intended for the non-healing wounds. Retrospective data will contain information about the subject's history and wound treatment by SoC. Prospective data will contain information about wound treatment by AMNIODERM+®.

NCT ID: NCT06439667 Not yet recruiting - Diabetic Foot Ulcer Clinical Trials

VIRTUALLY SUPERVISED TELE-EXERCISE PLATFORM FOR ACCELERATING PLANTAR WOUND HEALING

Tele-foot X
Start date: September 3, 2024
Phase:
Study type: Observational

The purpose of the study is design and use a telemedicine platform which integrates video-chat, pre-programmed interactive game-based foot, and ankle exercise modules, and real-time quantitative performance metrics displayed to the clinician to improve patient's perfusion to the lower extremity, improve diabetic wound healing and prevent muscle loss in the lower extremity.This is a cross sectional and comparative feasibility study. It is designed to explore acceptability, feasibility and proof of concept/ .

NCT ID: NCT06437028 Not yet recruiting - Diabetic Foot Ulcer Clinical Trials

Evaluating the Efficacy of Perinatal Membrane Allografts for the Treatment of Diabetic Foot Ulcers.

Start date: September 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn if using perinatal tissue allografts improves healing of chronic, non-healing foot ulcers in diabetic patients. The main question that this study aims to answer is: Does the use of perinatal tissue allografts in conjunction with standard of care wound management techniques result in a higher percentage of patients achieving complete wound closure (i.e. healing) as compared to patients being treated with standard of care alone after 6 and 12 weeks of treatment. One ulcer on each participant's foot will receive weekly 1) applications of perinatal tissue allografts and standard of care wound management or 2) standard of care wound management alone. Pictures of the ulcer and measurements of its size will be measured every week to track its healing progress over a total treatment period of 12 weeks. Additionally, the participants will be asked to fill out a questionnaire about the wound impacts their life.

NCT ID: NCT06434922 Completed - Quality of Life Clinical Trials

Prevention and Early Detection of Ulcer Recurrence in Patients With Type II Diabetes Mellitus

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to to evaluate the effectiveness of prevention strategies of recurrence in DFU's. It will also to detect the risk level of recurrence. The main question it aims to answer are: - Does intervention of prevention strategies effective to prevent the recurrence of DFU's? - How the risk level of the recurrence on DFU's patients? - How the impact of quality of life on DFU's patients? Researchers will compare intervention groups (receiving education covered various aspects, including they received guidance on foot examination, foot care, dietary habits, physical exercise, and stress management), and control groups (received standards follow-up care provided by healthcare providers, including pamphlets outlining care for DM patients based on the five pillars, including DM management, medication adherence, dietary practices, physical exercise routines, and foot care). Participants will: - For intervention group will be educated every month - Data for both intervention and control groups were collected monthly until three months.