Dexmedetomidine Clinical Trial
Official title:
The Effect of Intrathecal Versus Intravenous Dexmeditomedine on Postoperative Analgesia in Transurethral Resection of the Prostate
This study is to evaluate The analgesic effect of intrathecal versus intravenous dexmeditomedine in transurethral resection of the prostate
Status | Not yet recruiting |
Enrollment | 75 |
Est. completion date | June 26, 2021 |
Est. primary completion date | April 26, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 59 Years to 70 Years |
Eligibility | Inclusion Criteria: - male gender - 50:70years old - ASA:I,II Exclusion Criteria: - contraindications of spinal anesthesia - Patient refusal - Patient taking alpha agonist or antagonist - Uncontrolled cardiac diseases - Allergy to local anesthetic drugs |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Tanta University |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The time to first rescue analgesic | The duration between the administration of spinal block and the first desire for supplemental analgesia (onset of 1st post-operative analgesic dose).
First post-operative analgesic dose will be1 µg/kg intravenous fentanyl when visual analogue pain score (VAS) is 4 or more |
24 hours postoperative | |
Secondary | Postoperative pain score Total dose of analgesic consumption I the first postoperative day Intraoperative and postoperative complications | Visual analogue score (VAS) between 0 and 10{0= no pain, 10=most severe pain} | 24 hours postoperative | |
Secondary | Total analgesic consumption | The pain score will be assessed every 4 h in 24 h and fentanyl will be given in a dose of 1 µg /kg when Visual analogue score (VAS) is 4 or more. Any out breaking pain will be treated with increments of fentanyl in a dose of 0.5µg/kg. | 24 hours postoperative | |
Secondary | Intraoperative and postoperative complications | e.g. hypotension, bradycardia and vomiting | Intraoperative and 24 hours postoperative |
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