Dexmedetomidine as Adjuvant for FNB in TKA

Status Completed

Clinical Trial Summary

The aim of the study was to find out whether addition of dexmedetomidine to lower concentration of ropivacaine preoperatively in femoral nerve block (FNB) would intensify analgesia and preserve quadriceps muscle strength after TKA.

Clinical Trial Description

We designed this study to evaluate whether dexmedetomidine added to lower concentration of ropivacaine for FNB can intensify analgesic effect and meanwhile reduce the possibility of lower limb (or quadriceps) weakness. Three groups were compared: 0.2% ropivacaine (H group), 0.1% ropivacaine (L group) and ropivacaine 0.1% added with 2 μg/kg dexmedetomidine (LD group). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03658421
Study type	Interventional
Source	First Affiliated Hospital, Sun Yat-Sen University
Contact
Status	Completed
Phase	N/A
Start date	September 1, 2018
Completion date	November 10, 2018

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