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Dexmedetomidine clinical trials

View clinical trials related to Dexmedetomidine.

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NCT ID: NCT06431178 Recruiting - General Anesthesia Clinical Trials

General Anesthesia Versus Sedation By Dexmedetomidine and Ketamine With Local Infiltration for Percutaneous Transcatheter Closure of Atrial Septal Defect in Pediatric Patients

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The aim of the present study is to compare between general anesthesia versus sedation with dexmedetomidine and ketamine with local infilteration at the catheter insertion site in pediatric patients undergoing transcutaneous closure of atrial septal defect on hemodynamic changes.

NCT ID: NCT06399185 Recruiting - Dexmedetomidine Clinical Trials

Effect of Dexmedetomidine and Esketamine on Catheter-related Bladder Discomfort

Start date: June 6, 2024
Phase: Phase 4
Study type: Interventional

Catheter-related bladder discomfort (CRBD) is common in patients awaking from general anesthesia with an urinary catheter. We suppose that that use of dexmedetomidine and/or esketamine during anesthesia may reduce the occurrence of CRBD. This 2x2 factorial randomized trial is designed to explore the effects of esketamine, dexmedetomidine, and their combination on the occurrence CRBD in patients undergoing transurethral urological surgery.

NCT ID: NCT06386783 Recruiting - Dexmedetomidine Clinical Trials

Fentanyl Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Spinal Anesthesia ; Peritoneal Symptomatic Effects

Start date: July 1, 2023
Phase: Phase 3
Study type: Interventional

To compare whether 5 μg dexmedetomidine with 25 μg fentanyl added to 0.5% hyperbaric bupivacaine as adjuvants in spinal anaesthesia in patients undergoing appendectomy could reduce intraoperative peritoneal related symptoms.

NCT ID: NCT06386770 Recruiting - Dexmedetomidine Clinical Trials

Systemic Versus Local Dexmedetomidine as An Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Block

Start date: February 1, 2023
Phase: Phase 3
Study type: Interventional

The aim of this study is to investigate the analgesic effect of local versus systemic dexamedetomedine as adjuvant to bupivacaine in erector spinae block in kidney exploration surgeries.

NCT ID: NCT06352593 Recruiting - Dexmedetomidine Clinical Trials

Intraoperative Dexmedetomidine Infusion in Endovascular Intervention for Aneurysmal Subarachnoid Hemorrhage

Start date: April 6, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the role of intraoperative dexmedetomidine infusion in endovascular intervention for aneurysmal subarachnoid hemorrhage.

NCT ID: NCT06331182 Recruiting - Dexmedetomidine Clinical Trials

Dexmedetomidine and Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain

Start date: March 26, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to compare the role of dexmedetomidine and ketamine as an adjuvant in external oblique intercostal plane block for post thoracotomy pain.

NCT ID: NCT06327399 Recruiting - Dexmedetomidine Clinical Trials

Dexmedetomidine Infusion Dose Versus Rapid Bolus Dose Before Tracheal Intubation.

Start date: January 21, 2024
Phase: Phase 2
Study type: Interventional

Dexmedetomidine bolus dose may provide similar or less hemodynamic changes (less bradycardia and less hypertension) than infusion dose during induction of anaesthesia and tracheal intubation.

NCT ID: NCT06229054 Recruiting - Dexmedetomidine Clinical Trials

Dexmedetomidine in Obturator Nerve Block as an Analgesic in Transurethral Surgeries

Start date: February 1, 2024
Phase: Early Phase 1
Study type: Interventional

in our study, we will investigate the impact of adding dexmedetomidine to bupivacaine for the potency of the obturator nerve block and prevention of the postoperative pain associated with transurethral surgery in comparison of obturator nerve block with bupivacaine alone

NCT ID: NCT06210061 Recruiting - Dexmedetomidine Clinical Trials

Propofol-Fentanyl-Dexmedetomidine and Propofol-Fentanyl-Sevoflurane Anesthesia for Major Spine Surgery Under Somato Sensory- and Motor- Evoked Potential Monitoring

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the effect of adding dexmedetomidine on evoked potentials in adult patients undergoing spinal surgery under intravenous anesthesia

NCT ID: NCT06207331 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Effects of Atomized Dexmedetomidine on Lung Function in Patients With Chronic Obstructive Pulmonary Disease

Start date: October 28, 2023
Phase: N/A
Study type: Interventional

Studies have shown that intravenous infusion and nebulized dexmedetomidine can improve lung function in mechanically ventilated patients, including those with preoperative COPD, exerting lung protection. However, these studies are based on mechanical ventilation patients under general anesthesia, and more intuitive research is needed on whether dexmedetomidine can also exercise pulmonary precaution in awake patients. Pulmonary function monitoring is the most direct way to evaluate changes in lung function in awake patients. Portable pulmonary function machines can assess lung function in a variety of settings. In addition, compared with intravenous administration, nebulized inhalation administration directly acts on the mucosa of the respiratory tract, does not involve invasive operations, and has higher safety and comfort. Therefore, this study intends to use portable pulmonary function instruments and non-invasive ambulatory respiratory monitors to evaluate the effect of nebulized dexmedetomidine on lung function in COPD patients to guide the perioperative management of COPD patients.