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Development, Child clinical trials

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NCT ID: NCT06448520 Not yet recruiting - Activity, Motor Clinical Trials

Reference Values for the Muscle Power Sprint Test

Ref MPST
Start date: September 2024
Phase: N/A
Study type: Interventional

The goal of this prospective, cross-sectional study is to develop updated reference values for the Muscle Power Sprint Test (MPST) in children aged 5-12 years. The main question it aims to answer is: • What are reference ('normal') values for the MPST in children aged 5-12 years? Participants will be asked to perform six short sprints of fifteen meters each, with a ten-second rest between each effort.

NCT ID: NCT06365164 Not yet recruiting - Premature Clinical Trials

Study of the Emergence of Sensory Self-awareness in Premature Newborns Using the Rooting Reflex

PREMATACT
Start date: June 2024
Phase:
Study type: Observational

The main objective is to demonstrate the presence of the rooting reflex in premature and the emergence of sensory self-awareness in premature by showing a difference in the response of the rooting reflex to external tactile stimulation and to facilitated tactile self-stimulation during quiet wakefulness. The main hypothesis is to confirm the tactile skills of the very premature newborn in exploring the rooting reflex and then to evaluate the emergence of sensory self-awareness. The investigators assume a difference in response in favour of a greater response of the newborn to external tactile stimulation compared to facilitated self-stimulation in favour of the distinction between self and non-self showing the emergence of a sensory awareness of self in the preterm newborn.

NCT ID: NCT06157697 Not yet recruiting - Breastfeeding Clinical Trials

Social Transfers for Exclusive Breastfeeding in Brazil

STEBB
Start date: August 2024
Phase: N/A
Study type: Interventional

The goal of this study is to assess the effectiveness of social transfers on exclusive breastfeeding rates in São Paulo, Brazil. The main research questions are: 1. Are social transfers effective at increasing exclusive breastfeeding rates 2. Are social transfers effective in prolonging the duration of exclusive breastfeeding 3. What are the long-term impacts of social transfers for breastfeeding on child health and development Participants will be randomly assigned to one of three groups: 1) control, no social transfer 2) non-conditional social transfer at 6-months postpartum, and 3) conditional social transfer at six months postpartum; conditional upon the mothers exclusive breastfeeding status. All participants receive education about the benefits of exclusive breastfeeding and current international recommendations. Researchers will compare the intervention groups to the control group to see if social transfers are effective at increasing exclusive breastfeeding rates at six months postpartum.

NCT ID: NCT05779904 Not yet recruiting - Nutrition Clinical Trials

Methylation, mIcrobiome, NUtritional sTatus, and dEvelopment of Stunted Children

MINUTES
Start date: March 31, 2023
Phase:
Study type: Observational

The investigators will conduct a case-control study among under-two children in Lombok Timur, West Nusa Tenggara, Indonesia. The power required to detect changes in epigenetic markers may not be sufficient in the cohort study. Therefore, specific case-control design of stunted vs non-stunted children will provide the required power to detect potential epigenetic markers which will be further investigated through targeted sequencing of the cohort study. A total of 150 stunted children will be recruited and then it will be matched with 150 non-stunted children with the same sex. The assessments for these study subjects will include: 1) The genetic and epigenetic profile of the children, gut microbiota and nutritional status (Physical component), 2) Food security, Water, Sanitation and Hygiene (WASH) and Infant and Young Child Feeding (IYCF) practices (Home-Food component), 3) Children's psychosocial care and cognitive outcome (Cognition component).

NCT ID: NCT05243901 Not yet recruiting - Development, Child Clinical Trials

EPIPAGE 2 - 10-year Follow-up (RECONAI PROJECT)

EPIPAGE2
Start date: February 2022
Phase:
Study type: Observational

Epipage 2 (Epidemiological study on small gestational ages) is a prospective population-based national cohort implemented to better understand the short, mid and long term future of premature children. This study was launched on 28 March 2011 by the researchers of the EPOPé team (Perinatal, Obstetric and Pediatric Epidemiology Research) of the Epidemiology and Biostatistics Research Centre (INSERM U1153), in collaboration with the Inserm 1027 Unit (Epidemiology and Analysis in Public Health: risks, chronic diseases and handicaps) and medical teams of public health and research in 25 French regions. The study focuses on children born before 35 weeks of amenorrhea. 3 follow-up steps for children included in the cohort have already been completed at 1, 2 and 5 and a half years of age. Currently, nearly 4,000 children are still eligible for follow-up. Since the children are 9 years old, the follow-up steps are shared with those set up in another birth cohort, the Elfe cohort (Étude Longitudinale Française depuis l'Enfance, (www.elfe-france.fr) ), as part of the RE-CO-NAI project. The RE-CO-NAI project is a research platform on cohorts of children followed since birth in order to be able to study in a global and multidisciplinary way the major issues of the health, development and socialization of children. This RE-CO-NAI project was funded by the EQUIPEX 2011 call for projects as part of future investments. This protocol, which is part of the RECONAI project, concerns the fully shared follow-up phase, proposed in the 10th year for the children of the two cohorts.

NCT ID: NCT03742310 Not yet recruiting - Development, Child Clinical Trials

The Relationship Between VDR Gene Polymorphism and Children's Physical and Intellectual Development

RVDRGPCPID
Start date: January 1, 2019
Phase: N/A
Study type: Interventional

This study was used to determine the relationship between vitamin D receptor gene polymorphism and children's physical and intellectual development, further adjust the doses of vitamin D supplementation after birth, and provide individualized vitamin D and calcium supplements.