Detrusor Overactivity Clinical Trial
Official title:
Prevalence of Urodynamic Stress Incontinence and/or Detrusor Overactivity in Women With Cystocele and the Changes of Continence Function After Cystocele Repair
Verified date | July 2021 |
Source | National Taiwan University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The changes of lower urinary tract function after cystocele repair are important for perioperative consultation and management. Thus, the aim of this retrospective study was to evaluate the prevalence of urodynamic stress incontinence and/or detrusor overactivity in women with ≥ stage II cystocele and the changes of incontinence function after cystocele repair.
Status | Completed |
Enrollment | 483 |
Est. completion date | October 31, 2020 |
Est. primary completion date | October 31, 2020 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 20 Years to 85 Years |
Eligibility | Inclusion Criteria: - Women with = stage II cystocele - Received cystocele repair - Complete urodynamic study before and after surgery Exclusion Criteria: - Incomplete data - Chronic infection - Recurrent surgery for cystocele |
Country | Name | City | State |
---|---|---|---|
Taiwan | National Taiwan University Hospital | Taipei |
Lead Sponsor | Collaborator |
---|---|
National Taiwan University Hospital |
Taiwan,
Haylen BT, de Ridder D, Freeman RM, Swift SE, Berghmans B, Lee J, Monga A, Petri E, Rizk DE, Sand PK, Schaer GN; International Urogynecological Association; International Continence Society. An International Urogynecological Association (IUGA)/Internation — View Citation
Hsiao SM, Chang TC, Wu PC, Lin HH. Predictors of an improvement in the severity of concomitant urodynamic stress incontinence after transvaginal mesh surgery for pelvic organ prolapse. J Formos Med Assoc. 2020 May;119(5):917-924. doi: 10.1016/j.jfma.2019. — View Citation
Hsiao SM, Lin HH, Kuo HC. Videourodynamic Studies of Women with Voiding Dysfunction. Sci Rep. 2017 Jul 28;7(1):6845. doi: 10.1038/s41598-017-07163-2. — View Citation
Huang WC, Yang SH, Yang JM. Clinical Importance and Surgical Outcomes of Green Type III Cystocele in Women With Anterior Vaginal Prolapse. J Ultrasound Med. 2015 Dec;34(12):2279-85. doi: 10.7863/ultra.14.11066. Epub 2015 Nov 16. — View Citation
Lamblin G, Delorme E, Cosson M, Rubod C. Cystocele and functional anatomy of the pelvic floor: review and update of the various theories. Int Urogynecol J. 2016 Sep;27(9):1297-305. doi: 10.1007/s00192-015-2832-4. Epub 2015 Sep 4. Review. — View Citation
Leron E, Weintraub AY, Mastrolia SA, Schwarzman P. Overactive Bladder Syndrome: Evaluation and Management. Curr Urol. 2018 Mar;11(3):117-125. doi: 10.1159/000447205. Epub 2018 Feb 20. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Urodynamic stress incontinence | the finding of involuntary leakage during filling cystometry or stress urethral pressure profile, associated with increased intra-abdominal pressure, in the absence of a detrusor contraction | November 2010 and October 2020 | |
Primary | Detrusor overactivity | the occurrence of involuntary detrusor contractions during filling cytometry | November 2010 and October 2020 |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04543552 -
A Comparative Analysis of Portable Bladder Scanner to Determine Age/ Volume Specific Accuracy in 0-6 Years of Children
|
||
Not yet recruiting |
NCT04693897 -
Effect of beta3-adrenoceptor Agonist on Patients With Overactive Bladder and as a Urinary Biomarker
|
||
Enrolling by invitation |
NCT00822913 -
Botulinum A Toxin in Patients With Parkinson's Disease
|
Phase 4 | |
Terminated |
NCT00373789 -
Refractory Urge Incontinence and Botox Injections
|
Phase 3 | |
Completed |
NCT01093534 -
Study of 2 Doses of Solifenacin Succinate in Female Subjects With Overactive Bladder.
|
Phase 4 | |
Completed |
NCT01003457 -
Ultrasonographic Bladder Wall Thickness and Different Forms of Detrusor Overactivity
|
N/A | |
Terminated |
NCT01023269 -
Efficacy Study of Pudendal Neuromodulation for the Treatment of Neurogenic Overactive Bladder
|
N/A | |
Not yet recruiting |
NCT05572918 -
Developing a Simple Test to Diagnose Overactive Bladder
|
||
Completed |
NCT01850706 -
UNGF Assessment in Patients With Detrusor Overactivity Undergoing Sacral Neuromodulation
|
N/A | |
Completed |
NCT00478881 -
A Study To Assess If 10 mg Vardenafil (BAY38-9456) Taken Twice Daily For 6 Weeks Has An Effect On Bladder Function
|
Phase 2 | |
Completed |
NCT00678795 -
A Parallel Group Study to Compare Sativex® With Placebo in the Treatment of Detrusor Overactivity in Patients With Multiple Sclerosis
|
Phase 3 |