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Clinical Trial Summary

Desmoid tumor is a benign neoplasm with an unpredictable course and a high rate of local recurrence if treated surgically. Therefore, over time the surgical approach has become conservative, preferring simple observation or medical therapy in case of disease progression through the use of hormonal therapy and low-dose chemotherapy. Since this neoplasm remains benign, our study aims to avoid chemotherapy in patients usually young through the use of a minimally invasive treatment such as cryotherapy.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05091255
Study type Interventional
Source Istituto Ortopedico Rizzoli
Contact Costantino Errani, MD
Phone 051-6366
Email costantino.errani@ior.it
Status Recruiting
Phase N/A
Start date May 20, 2021
Completion date January 1, 2027

See also
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Active, not recruiting NCT04871282 - A Study of AL102 in Patients With Progressing Desmoid Tumors Phase 2/Phase 3
Recruiting NCT05284305 - Desmoid Tumor and Pregnancy: Effect of Pregnancy on Disease Control and Effect of Diagnosis on Pregnancy History.
Active, not recruiting NCT01273168 - Endoxifen in Adults With Hormone Receptor Positive Solid Tumors Phase 1
Recruiting NCT06268457 - Arterial Chemoembolization for the Treatment of Desmoid Fibromatosis
Recruiting NCT06224283 - Radiomics Compared With Conventional Response Criteria for Predicting Progression of Desmoid Tumor After Cryoablation
Withdrawn NCT02557854 - HIFU Hyperthermia With Liposomal Doxorubicin (DOXIL) for Relapsed or Refractory Pediatric and Young Adult Solid Tumors Phase 1
Recruiting NCT05490667 - Clinical Study of Anlotinib Combined With Chemotherapy in the Treatment of Unresectable Advanced Desmoid Tumor N/A
Not yet recruiting NCT06355921 - A Prospective Clinical Study on the Safety and Efficacy of Radiofrequency Ablation for the Treatment of Patients With Desmoid Tumors N/A