Clinical Trials Logo

Clinical Trial Summary

Thirty patients with desmoid tumors (invasive fibromatosis) will be recruited in the Department of Bone and Soft Tissue, Henan Cancer Hospital. This is a prospective, multicenter, single-arm clinical study to evaluate the efficacy and safety of anlotinib combined with chemotherapy in the treatment of inoperable advanced desmoid tumors.


Clinical Trial Description

Thirty patients with desmoid tumor (invasive fibromatosis) will be recruited in the Department of Bone and Soft Tissue, Henan Cancer Hospital. This is a prospective, multicenter, single-arm clinical study to evaluate the efficacy and safety of anlotinib combined with chemotherapy in the treatment of inoperative advanced desmoid tumor. To evaluate the 6-month progression-free survival rate, 12-month progression-free survival rate, progression-free survival (PFS), objective response rate (ORR), disease control rate (DCR) and safety of anlotinib combined with chemotherapy for desmoid tumors. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05490667
Study type Interventional
Source Henan Cancer Hospital
Contact
Status Recruiting
Phase N/A
Start date August 20, 2022
Completion date July 31, 2024

See also
  Status Clinical Trial Phase
Completed NCT03966742 - Doxorubicin Eluting Intra-arterial Embolization for Aggressive Desmoid Fibromatosis Phase 2
Completed NCT03275818 - Trial of Nab-paclitaxel in Patients With Desmoid Tumors and Multiply Relapsed/Refractory Desmoplastic Small Round Cell Tumors and Ewing Sarcoma Phase 2
Recruiting NCT05091255 - Cryotherapy in the Treatment of Desmoid Tumors N/A
Active, not recruiting NCT04871282 - A Study of AL102 in Patients With Progressing Desmoid Tumors Phase 2/Phase 3
Recruiting NCT05284305 - Desmoid Tumor and Pregnancy: Effect of Pregnancy on Disease Control and Effect of Diagnosis on Pregnancy History.
Active, not recruiting NCT01273168 - Endoxifen in Adults With Hormone Receptor Positive Solid Tumors Phase 1
Recruiting NCT06268457 - Arterial Chemoembolization for the Treatment of Desmoid Fibromatosis
Recruiting NCT06224283 - Radiomics Compared With Conventional Response Criteria for Predicting Progression of Desmoid Tumor After Cryoablation
Withdrawn NCT02557854 - HIFU Hyperthermia With Liposomal Doxorubicin (DOXIL) for Relapsed or Refractory Pediatric and Young Adult Solid Tumors Phase 1
Not yet recruiting NCT06355921 - A Prospective Clinical Study on the Safety and Efficacy of Radiofrequency Ablation for the Treatment of Patients With Desmoid Tumors N/A