Desmoid Tumor Clinical Trial
Official title:
RINGSIDE: A Phase 2/3, Randomized, Multicenter Study to Evaluate AL102 in Patients With Progressing Desmoid Tumors
The current study is designed to evaluate the efficacy and safety of AL102 in patients with progressive desmoid tumors.
This is a Phase 2/3, randomized study in subjects with progressive desmoid tumors consisting of 2 parts. Phase2/Part A is an open-label, dose regimen finding study; Phase3/Part B is a double blind, placebo-controlled study and Open Label Extension utilizing the dose regimen selected in Phase2/Part A. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05561036 -
A Randomized, Double-blind,Phase Ⅲ Study of Liposome Doxorubicin in Desmoid Tumor
|
Phase 3 | |
Completed |
NCT00287846 -
Imatinib Mesylate in Treating Patients With Recurrent or Refractory Fibromatosis
|
Phase 1/Phase 2 | |
Recruiting |
NCT06258421 -
Burden of Disease and Living Situation in Desmoid Patients
|
||
Completed |
NCT00030680 -
Radiation Therapy in Treating Patients With Aggressive Fibromatoses
|
Phase 2 | |
Recruiting |
NCT06081400 -
Cryoablation Versus Medical Therapy in Desmoid Tumors Progressing After Watchful Waiting
|
N/A | |
Recruiting |
NCT01567046 -
Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas
|
N/A | |
Completed |
NCT01137916 -
Study to Evaluate Imatinib in Desmoid Tumors
|
Phase 2 | |
Completed |
NCT00002595 -
Toremifene in Treating Patients With Desmoid Tumors
|
Phase 2 | |
Completed |
NCT03459469 -
Phase I, Open-label, Non-randomized Study to Evaluate Safety of BC2059
|
Phase 1 | |
Completed |
NCT06195085 -
CT-guided Radioactive Iodine-125 Seed Implantation for Recurrent Desmoid Tumors
|
||
Completed |
NCT01286662 -
A Cohort Study of Patients Treated With Brachytherapy for Selected Desmoid Patients in Gardner Syndrome
|
N/A | |
Completed |
NCT01265030 -
A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis
|
Phase 1/Phase 2 | |
Completed |
NCT00068419 -
Sulindac and Tamoxifen in Treating Patients With Desmoid Tumor
|
Phase 2 | |
Completed |
NCT04289077 -
Quality of Life of Patients With Desmoid-type Fibromatosis
|
||
Completed |
NCT03190174 -
Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers
|
Phase 1/Phase 2 | |
Completed |
NCT00003019 -
Vinblastine and Methotrexate in Treating Children With Desmoid Tumors
|
Phase 2 | |
Recruiting |
NCT05949099 -
Study of Cryoablation and Nirogacestat for Desmoid Tumor
|
Phase 2 | |
Active, not recruiting |
NCT02076906 -
MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors
|
Phase 1 | |
Completed |
NCT00474994 -
Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas
|
Phase 2 | |
Active, not recruiting |
NCT03785964 -
Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)
|
Phase 3 |