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Study of Cryoablation and Nirogacestat for Desmoid Tumor

Desmoid Tumor Clinical Trial

Official title:
Phase II Study of Cryoablation and Nirogacestat for Desmoid Tumor

Clinical Trial Summary

The primary purpose of this protocol is Systemic therapy with oral study agent, nirogacestat, followed by a single cryoablation procedure.

Clinical Trial Description

The primary purpose of this protocol is treatment. Systemic therapy with oral study agent, nirogacestat, will be given for 3 cycles (1 cycle = 28 days) followed by a single cryoablation procedure between Cycles 3 and 4, and then continued nirogacestat for Cycles 4 through 26. Treatment with nirogacestat may continue via this study for up to 24 months (26 cycles of treatment), unless there is progression of disease, intolerance, subject withdraws their consent, start of a new anticancer therapy, or until Subject Study Completion or Termination occurs. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05949099
Study type Interventional
Source Stanford University
Contact Behnaz P Agahian
Phone 650-498-0623
Email behnaza@stanford.edu
Status Recruiting
Phase Phase 2
Start date August 15, 2023
Completion date February 1, 2028
View Details
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