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Dermatitis clinical trials

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NCT ID: NCT02941432 Completed - Eczema, Dermatitis Clinical Trials

Black Tea Compresses for Facial Eczema and Perioral Dermatitis

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

Facial eczema and perioral dermatitis are clinical entities that develop exclusively in the face and present a special therapeutic challenge. Topical corticosteroids that are commonly applied to treat eczema/dermatitis at other body sites are best avoided in the face, as they may result in rapid atrophy of facial skin and in the long term rather aggravate facial dermatoses. Black tea compresses have been successfully used by German-speaking dermatologists to treat facial eczema/dermatitis for decades. The precise mechanism of action is unknown but is presumably based on astringent properties of tannins in the black tea and on the antiinflammatory action of a wet compress as such. This therapy is cheap, universally available and practically free of side-effects. Despite these perceived advantages the effects and tolerance of black tea compresses have not been formally studied to date. Therefore, the investigators plan to treat 25 patients with facial eczema/perioral dermatitis over a period of 6 days each within the current trial. The disease activity will be assessed before, during and after completion of treatment using several clinical scores. In addition, side-effects, if any, will be documented.

NCT ID: NCT02932891 Completed - Atopic Dermatitis Clinical Trials

An Open Label, Safety Study to Assess the Potential for Adrenal Suppression.

Start date: August 2016
Phase: Phase 2
Study type: Interventional

An Open Label, Safety Study to Assess the Potential for Adrenal Suppression Following Treatment with DSXS in Patients with Atopic Dermatitis

NCT ID: NCT02926807 Completed - Atopic Dermatitis Clinical Trials

Trial on Vascular Inflammation in Atopic Dermatitis

Start date: January 2017
Phase:
Study type: Observational

A total of 30 subjects with moderate to severe atopic dermatitis. Thirty subjects without AD matched for sex, age and coronary artery disease risk factor with the AD subjects will also be included. All subjects will undergo the following imaging procedures: a 18FDG-PET to quantify vascular inflammation in the ascending aorta and carotids and a MDCT to calculate the Agatston score. Skin and blood biomarkers will also be assessed.

NCT ID: NCT02925793 Completed - Atopic Dermatitis Clinical Trials

Safety and Efficacy Study of Topically Applied DS107 Cream in Mild to Moderate Atopic Dermatitis Patients (AD)

Start date: December 2016
Phase: Phase 2
Study type: Interventional

The purpose of this randomized, double blind, placebo controlled, parallel group study is to compare the safety and efficacy of topically applied DS107 cream (1% and 5%) versus vehicle cream, in the treatment of adult patients with mild to moderate Atopic Dermatitis (AD).

NCT ID: NCT02925117 Completed - Atopic Dermatitis Clinical Trials

A Study to Evaluate ABT-494 (Upadacitinib) in Adults With Moderate to Severe Atopic Dermatitis

Start date: October 25, 2016
Phase: Phase 2
Study type: Interventional

The objective of this study was to evaluate the safety and efficacy of multiple doses of upadacitinib monotherapy versus placebo in the treatment of adults with moderate to severe atopic dermatitis (AD).

NCT ID: NCT02922244 Completed - Breast Neoplasms Clinical Trials

Effects of Herbal Products on Reduction of Radiation-induced Dermatitis in Breast Cancer Patients

Start date: May 2016
Phase: N/A
Study type: Interventional

The herbal products on reduction of radiation-induced dermatitis in patients with breast cancer

NCT ID: NCT02920411 Completed - Atopic Dermatitis Clinical Trials

Effectiveness of a Combined Dermatological Treatment in Children With Atopic Dermatitis

KAOS
Start date: October 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effectiveness of a combined dermatological treatment in children up to 5 years old with mild or moderated atopic dermatitis.

NCT ID: NCT02916888 Completed - Dermatitis, Atopic Clinical Trials

A Study Comparing the Quality of Life of Patients in the Treatment of Eczema by Pediatric Generalists and Specialists

Start date: September 2016
Phase: N/A
Study type: Observational

The purpose of this study is to investigate the differences in the quality of life of patients and caregivers who are treated by general pediatricians versus pediatric dermatologists for eczema (atopic dermatitis or AD).

NCT ID: NCT02914548 Completed - Atopic Dermatitis Clinical Trials

Study of OPA-15406 Ointment in Patients With Atopic Dermatitis

Start date: September 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of OPA-15406 ointment in patients with atopic dermatitis.

NCT ID: NCT02910011 Completed - Dermatitis, Atopic Clinical Trials

Topical NanoDox® for Atopic Dermatitis

Start date: May 18, 2017
Phase: Phase 2
Study type: Interventional

This study will investigate the safety and clinical efficacy of a novel doxycycline topical formulation in subjects with Atopic Dermatitis (AD). The investigators hypothesize that daily application of the study drug in AD subjects will reduce severity of the disease, by reducing skin driven inflammation and restoring skin barrier function. The investigators will also monitor the anti-microbial activity of this product on AD skin, as colonization with Staph aureus is typically associated with disease severity.