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Dermatitis, Atopic clinical trials

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NCT ID: NCT04110873 Terminated - Atopic Dermatitis Clinical Trials

A Phase II, Placebo-controlled Trial Evaluating the Efficacy of Antroquinonol in Patients With Atopic Dermatitis

Start date: July 27, 2018
Phase: Phase 2
Study type: Interventional

Primary Objective: To evaluate the activity of Antroquinonol in patients with atopic dermatitis. Secondary Objective: To assess the mechanism and cytokines change of Antroquinonol in patients with atopic dermatitis. Exploratory Objective: To explore potential relationships between Antroquinonol exposure and safety and efficacy endpoints.

NCT ID: NCT04097327 Completed - Clinical trials for Atopic Dermatitis Eczema

Effect of Ectoin Dermatitis Cream 7% on Skin Hydration and Skin Barrier Function

Start date: August 23, 2019
Phase:
Study type: Observational

The aim of this prospective, uncontrolled clinical study is to evaluate the clinical effect of Ectoin® Dermatitis Cream-EHK02 on skin hydration and transepidermal water loss (TEWL) in subjects with atopic dermatitis after single and multiple applications. Furthermore, data concerning the subjective impression of the study preparation should be collected.

NCT ID: NCT04090229 Completed - Atopic Dermatitis Clinical Trials

A Multi-center, Randomized, Double-blind, Placebo-controlled, Multiple Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of Subcutaneously Delivered ASLAN004 in Adults With Moderate-Severe Atopic Dermatitis

Start date: September 9, 2019
Phase: Phase 1
Study type: Interventional

A Phase 1B, multi-center, double-blind, placebo-controlled, randomized, multiple ascending dose (MAD) clinical study is designed to evaluate ASLAN004 versus placebo in patients who have moderate-severe AD. The treatment period duration will be 8 weeks with a 12-week follow-up period after the end of treatment.

NCT ID: NCT04087863 Recruiting - Atopic Dermatitis Clinical Trials

Administration for Placebo Group and Evalution the Safety and Efficacy in Atopic Dermatitis Patients

Start date: August 29, 2019
Phase:
Study type: Observational

A Multi-center, Open, Single-arm Clinical Trial to Evaluate the Safety and Efficacy of FURESTEM-AD inj. in Patients with Moderate to Severe Chronic Atopic Dermatitis Who Participated in a Placebo Group in K0102 Clinical Trial: 2nd Extension Study of K0102

NCT ID: NCT04086121 Terminated - Dermatitis, Atopic Clinical Trials

A Study to Test the Long-term Safety of BI 655130 in Patients With Atopic Eczema Who Took Part in Study 1368-0032

Start date: September 24, 2019
Phase: Phase 2
Study type: Interventional

To assess the long term safety and efficacy of treatment with BI 655130 in patients with AD who have completed and have responded to treatment in the parent study 1368-0032

NCT ID: NCT04085549 Terminated - Clinical trials for Atopic Dermatitis Eczema

Effects of a Berry Oil Cream on Atopic Eczema and Skin

Start date: October 9, 2019
Phase: N/A
Study type: Interventional

Atopic eczema is a chronic inflammatory skin disease associated with itch and inflammatory lesions in typical skin areas. The objective of this study is to investigate the effects of a cream containing berry and plant oils and humectants on atopic eczema and dry skin.

NCT ID: NCT04081350 Completed - Dermatitis, Atopic Clinical Trials

A Study of LY3471851 in Participants With Eczema

Start date: December 4, 2019
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to learn more about the safety and side effects of LY3471851 when given by injection just under the skin to participants with eczema. The study will last up to 48 weeks and may include up to 23 visits to the study center.

NCT ID: NCT04066998 Not yet recruiting - Atopic Dermatitis Clinical Trials

Cytokine Profile of Conjunctivitis, Performed Through Tears Analysis Among Patients Treated With Dupilumab

CYCLADDE
Start date: December 2019
Phase: N/A
Study type: Interventional

This study aims to assess the cytokine profile of tears in patients suffering from conjunctivitis versus patients without ocular involvement, when treated with Dupilumab

NCT ID: NCT04065633 Completed - Dermatitis, Atopic Clinical Trials

Study of Commercial and Phase 3 of PF-04965842 Formulations, Estimation of Effect of Food on Commercial Formulation

Start date: July 18, 2019
Phase: Phase 1
Study type: Interventional

Part A - To measure and compare the amount of study drug in the blood after a single 200 mg dose of study drug given as the commercial tablet formulation and the Phase 3 tablet formulation under fasting conditions - To measure and compare the amount of study drug in the blood after a single 200 mg dose given as the variant Phase 3 tablet formulation and the Phase 3 tablet formulation under fasting conditions - To estimate the effect of food on the amount of study drug in the blood after a single 200 mg dose of the commercial formulation Part B • To measure and compare the amount of study drug in the blood after a single 200 mg dose given as the commercial tablet formulation and the Phase 3 tablet formulation under fasting conditions Parts A & B - To collect samples for genotyping (CYP2C19 and CYP2C9 - enzymes that metabolize [break down] certain medications) o Genotyping is the collection of a small sample of blood that contains your genes - To evaluate the safety and tolerability of the study drug after single 200 mg doses of the three different formulations given to healthy participants - To measure the amount of study drug in the blood after single doses of the different formulations - To collect exploratory samples for biobanking o Biobanking is the collection and storage of blood samples for possible future testing

NCT ID: NCT04060550 Recruiting - Clinical trials for Atopic Dermatitis Without a History of Eczema Herpeticum

Impact of Increased Immunoglobulin E to Anti-herpes Simplex Virus -1 Innate Immune Responses in Atopic Dermatitis Patients With Eczema Herpeticum

Start date: January 9, 2020
Phase:
Study type: Observational

This study investigates whether blood monocytes' surface bound- immunoglobulin E affects the innate immune responses against herpes simplex viruses in atopic dermatitis patients with eczema herpeticum.