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Dermatitis, Atopic clinical trials

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NCT ID: NCT05277571 Recruiting - Atopic Dermatitis Clinical Trials

A Single-ascending Dose (Part A) and Repeat-dose (Part B) Study to Investigate the Safety, Pharmacokinetics and Efficacy (Part B Only) of UCB1381 in Healthy Study Participants (Part A) and in Study Participants With Moderate to Severe Atopic Dermatitis (Part B)

Start date: March 7, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of the study is to investigate the safety and tolerability of single-ascending doses of UCB1381 (intravenous and subcutaneous) in healthy study participants and after repeat intravenous dosing in study participants with atopic dermatitis. Efficacy will be assessed following repeat intravenous dosing versus placebo in study participants with atopic dermatitis.

NCT ID: NCT05276323 Completed - Atopic Dermatitis Clinical Trials

Medihoney® Derma Cream Treatment for Mild to Moderate Atopic Dermatitis in Children Study

Start date: October 1, 2020
Phase: Phase 2
Study type: Interventional

A randomized, open-label trial comparing Medihoney Derma Cream to Hydrocortisone 1% cream. Children between the ages of 2-18 years old diagnosed with mild to moderate atopic dermatitis with an IGA (Investigator Global Assessment) score of 2-3, and a BSA (Body Surface Area) score of 1%-10% were included.

NCT ID: NCT05265923 Recruiting - Atopic Dermatitis Clinical Trials

A Study of CM310 in Patients With Moderate-to-Severe Atopic Dermatitis

Start date: April 22, 2022
Phase: Phase 3
Study type: Interventional

This is a multi-center, randomized, double blind, placebo-controlled phase 3 study to evaluate the efficacy, safety, PK, PD and immunogenicity of CM310 in patients with moderate-to-severe atopic dermatitis.

NCT ID: NCT05265234 Recruiting - Atopic Dermatitis Clinical Trials

Dupilmuab for Atopic Dermatitis Monitored With Noninvasive Imaging.

Start date: March 1, 2022
Phase: Phase 4
Study type: Interventional

The study is trying to answer the following question: "Can we use non-invasive imaging to evaluate the response of atopic dermatitis (eczema) to Dupixent (dupilumab)?"

NCT ID: NCT05259774 Completed - Atopic Dermatitis Clinical Trials

Clinical Investigation on the Efficacy and Safety of Relizema Cream in Paedriatric Patients

YOUNG
Start date: October 27, 2022
Phase: N/A
Study type: Interventional

The scope of this multicenter, double blind, randomized, vehicle-controlled clinical investigation is to evaluate and confirm the performance and safety of the Relizema cream in the improvement of the dermatitis severity in paediatric patients. The disease severity will be clinically measured through the Investigator Global Assessment (IGA) after 42 days of treatment.

NCT ID: NCT05253755 Terminated - Atopic Dermatitis Clinical Trials

Study the Safety and Efficacy of DBI-001 Gel Versus Aqueous Gel

Start date: October 6, 2021
Phase: Phase 2
Study type: Interventional

The purpose for this study is to assess the Safety and Efficacy of Daily Application for 4 weeks of DBI-001 Gel Versus Aqueous Gel in Subjects with Atopic Dermatitis

NCT ID: NCT05250115 Recruiting - Dermatitis, Atopic Clinical Trials

A Study to Learn About the Study Medicine (Called Abrocitinib) in Adult Patients With Moderate to Severe Atopic Dermatitis

Start date: May 10, 2022
Phase:
Study type: Observational [Patient Registry]

The purpose of this non-interventional observational study is to learn about the safety and effects of the medicinal product (called Abrocitinib) for the potential treatment of moderate to severe atopic dermatitis (AD). AD is a long-lasting disease that causes redness and irritation of the skin. This non-interventional study is seeking participants who is eligible for Abrocitinib treatment according to the summary of product characteristics (SmPC): - Are aged at least 18 years old - Have a confirmed diagnosis of AD by a skin doctor - Decide to start treatment with Abrocitinib as part of routine clinical practice - Have a personally signed and dated informed consent document. This is used to indicate that the patient has been informed of all pertinent aspects of the study and data privacy aspects Participants will take the medicinal product as prescribed in the real-world setting. We will examine the experiences of people receiving Abrocitinib. This will help us determine if the medicinal product is effective and safe. Participants will take part in this study for 3 months. During this time, participants will be followed up from the date of their first Abrocitinib prescription for 12 months. During this non-interventional study, some participants may switch to other therapies after their initial Abrocitinib therapy. We will follow these participants further when they switch therapy to monitor their experiences. Participant documentation is expected quarterly as per standard clinical practice.

NCT ID: NCT05240300 Not yet recruiting - Atopic Dermatitis Clinical Trials

A Study of Topical BX005-A in Subjects With Moderate to Severe Atopic Dermatitis

Start date: May 2022
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of study BMX-05-001 is to evaluate the safety, tolerability, efficacy, and pharmacodynamics of BX005-A compared to vehicle administered topically in adult subjects with moderate to severe atopic dermatitis (AD).

NCT ID: NCT05235724 Completed - Dermatitis Atopic Clinical Trials

A Study to Assess the Reliability/Feasibility of Using Emerald Touchless Sensor for Scratching and Sleep Quantification in a Subset of Participants From PEDISTAD Study (OBS15333; NCT03687359)

Start date: February 17, 2022
Phase:
Study type: Observational

Primary objective: To explore and quantify the association between nighttime scratching and sleep patterns objectively in pediatric participants with moderate to severe atopic dermatitis (AD) using an innovative Emerald touchless sensor. Secondary objective: To evaluate the feasibility of using the Emerald touchless sensor in a pediatric clinical trial setting.

NCT ID: NCT05226143 Completed - Dermatitis, Atopic Clinical Trials

A Study of an Eczema Spot Treatment in Providing Eczema Symptoms Relief and Lasting Itch Relief to Affected Skin Area

Start date: February 21, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy (assessed by clinical evaluation of eczema/atopic lesion severity [atopic dermatitis severity index {ADSI} scoring] and perceived benefits in itch [visual analog score {VAS} scoring]) and tolerability (assessed by clinical grading) of an investigational spot treatment Gel Cream when used on a target site of participants with mild to moderate atopic dermatitis.