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Depression in Remission clinical trials

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NCT ID: NCT06145984 Recruiting - Clinical trials for Depression in Remission

Mechanisms of Change of Positive Interventions in Reducing Vulnerability for Depression

MINDCOG
Start date: June 19, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to understand the effects of mindfulness and fantasizing in reducing perseverative cognition underlying vulnerability for depression.

NCT ID: NCT05585775 Recruiting - Depression Clinical Trials

Mood and Thought Process Study

MAT Process
Start date: April 6, 2023
Phase: N/A
Study type: Interventional

The primary objective for this project is to test whether affective executive functioning is a mechanism of action of mindfulness-based cognitive therapy and Wellness for Wellbeing. The main questions it aims to answer are: 1. Test the effect of MBCT vs. Wellness for Wellbeing on affective inhibition (i.e., emotionally valenced inhibition as measured via the affective Go/No Go task) using an RCT. 2. Test the effect of MBCT vs. Wellness for Wellbeing on (a) affective updating and (b) affective shifting. Outcomes will be measured with the affective n-Back and the affective Internal Switching Task, respectively. 3a) The investigators will examine whether depression symptom severity co-varies with change in affective executive functioning (i.e., affecting inhibition, shifting, and updating) over time. 3b) The investigators will examine whether compliance with treatment protocol (e.g., number of classes attended, amount of home practice) predicts endpoint executive functioning. Participants will complete surveys, interviews, and computer tasks, and will be randomized to either Mindfulness-Based Cognitive Therapy or Wellness for Wellbeing.

NCT ID: NCT04211467 Recruiting - Depression Clinical Trials

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Depression

Start date: March 2, 2020
Phase:
Study type: Observational

This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records

NCT ID: NCT02821975 Recruiting - Clinical trials for Depression in Remission

Cognitive Computer Training in Patients With Depression

Start date: December 2015
Phase: N/A
Study type: Interventional

Cognitive impairment plays an important role in functional recovery and leads to long-term sickness absence. Therefore there is a need of a treatment specifically improving cognitive functions. In this pilot study the investigators aim to evaluate the feasibility of using cognitive computer training in patients with unipolar depression to enhance cognitive performance. Further the investigators investigate whether this intervention shortens sick leave.