Clinical Trials Logo
  1. Home
  2. Dentin Hypersensitivity
  3. NCT04225247

Efficacy of Seventh Generation Bonding Agents as Short-Term Desensitizers Among Patients With Hypersensitivity

Dentin Hypersensitivity Clinical Trial

Official title:
Efficacy of Seventh Generation Bonding Agents as Short-Term Desensitizers Among Patients With Hypersensitivity A Randomized Clinical Trial

Clinical Trial Summary

The world lacks a gold standard treatment for treating dentin hypersensitivity. Fluoride varnish is most commonly used as a treatment but it causes temporary discoloration of tooth structure and may cause irritation or burning of gums when it comes in contact with gums. Seventh generation bonding agents are less technique sensitive and are easy to use. The present study aims to find out the better seventh generation bonding agent as a treatment option for sensitivity.

A total of 105 patients with dentin hypersensitivity are randomized into three groups. Scaling and root debridement are performed for all the groups. This study compares two seventh generation bonding agents and taking fluoride varnish as control group.

Clinical Trial Description

Dentin hypersensitivity is a painful condition resulting from external stimulation of exposed vital dentin. Dentin gets exposed to the oral environment by multiple factors like gingival recession, erosion, attrition, abrasion, fractures, caries, and many more. The intra-tubular fluid movement of exposed tubules is believed to be the mechanism of hypersensitivity. Dentin bonding agents acts by occluding patent tubules, thus reducing hypersensitivity. Seventh generation combines etchant, primer and bonding agent into one solution and makes it easy to use.

After diagnosis of dentin hypersensitivity, the patients signed a consent form stating their voluntary participation in the research. The discomfort internal scale score and Schiff cold air sensitivity scale scores are recorded at baseline, immediately after the intervention, after 01 week and after 01 month. Discomfort internal scale score are recorded for every participant using dental explorer in the mesial and distal direction on the exposed surface of the affected teeth for tactile stimulation. For schiff cold air sensitivity scale scores an air syringe system was used to check the evaporative response on the affected teeth of the participants and the scores are recorded.

All the patients received scaling and root debridement as a standard protocol treatment. Dentin bonding agents and fluoride varnish are applied to the participants. All the participants are instructed to fast for two hours after the treatment. All the records are made on subjective response of patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04225247
Study type Interventional
Source Dow University of Health Sciences
Contact
Status Completed
Phase Phase 3
Start date March 7, 2018
Completion date October 7, 2018
View Details
See also
  Status Clinical Trial Phase
Completed NCT04249336 - Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH Phase 3
Completed NCT00763269 - The Efficacy of a Toothpaste to Reduce Sensitivity Phase 3
Recruiting NCT06154941 - Clinical Evaluation of Giomer Based Varnish Versus CPP-ACP Varnish in the Management of Dentin Hypersensitivity: a Randomized Clinical Trial N/A
Completed NCT05501691 - Effect of Diode Laser on Sensitive NCCLs Prior to Composite Restoration N/A
Not yet recruiting NCT04484844 - Clinical Evaluation of Efficacy of Shield Force Plus Varnish VS Sodium Fluoride on Dentin Hypersensitivity Phase 2/Phase 3
Completed NCT02936830 - Effectiveness of Nanohydroxyapetite Paste on Reducing Dentin Hypersensitivity Phase 4
Completed NCT02931734 - Assessment of Different Protocols for Cervical Dentin Hypersensitivity Treatment N/A
Completed NCT04512625 - Desensitizers in Reducing Post Tooth Preparation Sensitivity for a Fixed Dental Prosthesis N/A
Completed NCT05623761 - Toothpastes With Thermal Water for Oral Health Phase 4
Not yet recruiting NCT04731766 - Effect of Using Different Varnishes on Dentin Hypersensitivity; Na Fluoride and Nano-silver Fluoride N/A
Recruiting NCT05927831 - Grape Seed Extract VS Low Level Laser Therapy for Dentin Hypersensitivity N/A
Completed NCT03943095 - Study to Characterize the Efficacy of a Dual Active Dentifrice for the Relief of Dentin Hypersensitivity Phase 2
Not yet recruiting NCT06276777 - The Effect of Using Desensitizers Containing S-PRG In Treatment Of Dentin Hypersensitivity Over 6 Months: A Randomized Clinical Trial N/A
Completed NCT04887181 - The Effects of Different Dentin Hypersensitivity Treatment Methods on Quality of Life N/A
Not yet recruiting NCT03061383 - Reduction of Dentine Hypersensitivity Using 8% Arginine Based Toothpaste and 8% Strontium Acetate Based Toothpaste (DH) N/A
Recruiting NCT03076944 - Evaluation of Desensitization Protocols in Reduction of Dentin Hypersensitivity N/A
Recruiting NCT06264453 - A Study to Evaluate the Efficacy and Safety of KH001 in Patients With Dentin Hypersensitivity Phase 2
Recruiting NCT03083496 - Clinical Evaluation of Different Potassium Oxalate Concentrations in Dentin Hypersensitivity Treatment N/A
Completed NCT03965039 - A Clinical Study to Assess the Effects of Various Dentifrice Technologies on Dentinal Hypersensitivity N/A
Completed NCT06113874 - The Influence of Desensitizing Agent on Postoperative Sensitivity in Posterior Composite Restoration N/A