Dental Plaque Clinical Trial
Official title:
Dental Office Prevention Strategies for Children: 10% Povidone Iodine (PI) Cleansing Prior to Fluoride Varnish (FV) Application
The overall goal of this study is to improve the standard of care in treating young children
who often suffer from chronic caries (dental decay). Current standard of care for children
under 12 years old includes a dental cleaning and fluoride treatment. Often this dental
cleaning includes a 'dental prophylaxis' with a pumice based paste delivered by a small
rubber-like cup that rotates on a slow-speed dental handpiece. The procedure of this dental
prophylaxis removes the gross levels of plaque around the supragingival tooth surfaces.
After this prophylaxis, a fluoride treatment is delivered. The National Maternal and Child
Oral Health Resource Center at Georgetown University has published (Bertness J, Holt K) an
extensive publication proving that 5% sodium fluoride varnish has become the 'standard of
care' for fluoride treatment in children. This study includes this fluoride standard of
care.
Prior to the administration of this standard of care fluoride treatment, a separate step of
cleansing the tooth after the dental prophylaxis is added. This study uses a cleansing
procedure of 10% povidone iodine (PI) cleansing prior to fluoride varnish (FV) application.
The primary aims of this study are:
1. to measure the changes in overall plaque levels after using a 10% povidone iodine (PI)
cleansing prior to fluoride varnish (FV) application.
2. to measure the short term changes in the oral microbial ecology of dental plaque after
10% povidone iodine (PI) cleansing prior to fluoride varnish (FV) application.
n/a
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04881357 -
Antiplaque/Antigingivitis Effect of Lacer Oros Integral
|
N/A | |
| Completed |
NCT04561960 -
Efficacy of Miswak in Oral Hygiene Maintenance
|
Phase 4 | |
| Completed |
NCT04025684 -
Efficacy of Manual Toothbrushes in Removing Dental Plaque
|
N/A | |
| Completed |
NCT03394729 -
Effect of a Propolis Tablet on the Saliva and the Amount of Adolescent Dental Plaque Microbes
|
Phase 2/Phase 3 | |
| Completed |
NCT05187507 -
Effectiveness of Theobromine Toothpaste
|
N/A | |
| Completed |
NCT04485520 -
Efficacy of the Extract of Carica Papaya as an Inhibitor of Streptococcus Mutans
|
N/A | |
| Completed |
NCT02552589 -
Effect of Toothpaste on the Reduction of Plaque and Inflammation
|
N/A | |
| Completed |
NCT02884817 -
Essential Oil+ELA, Plaque and Gingivitis
|
Phase 4 | |
| Completed |
NCT02194023 -
Clinical Effects of Two New Chlorhexidine Digluconate Formulations: 0.12% and 0.03%.
|
Phase 2 | |
| Completed |
NCT01237782 -
Efficacy of a Propolis-based Denture Cleanser
|
N/A | |
| Completed |
NCT00758394 -
Clinical Study to Compare Dental Plaque Control
|
Phase 3 | |
| Completed |
NCT00254345 -
Effect of Provisional-Crown Surface Coating on Biofilm Formation
|
Phase 1 | |
| Completed |
NCT05579938 -
Effect of Enzymes on Dental Biofilm Accumulation
|
N/A | |
| Completed |
NCT05038293 -
Efficacy of Plaque Removal of a Novel Brushing Device
|
N/A | |
| Terminated |
NCT05082103 -
Effect of Enzymes on Dental Biofilm Accumulation in Healthy Individuals
|
N/A | |
| Not yet recruiting |
NCT06081868 -
RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda
|
N/A | |
| Completed |
NCT05853679 -
Regular Antibacterial Photodynamic Therapy on Oral Hygiene in Elderly Residents
|
N/A | |
| Completed |
NCT05521230 -
Short-Term Anti-plaque Effect of Cymenol Mouthwash Analysed Using Dentius Deep Plaque Software
|
Phase 1 | |
| Completed |
NCT03311438 -
Oral Health Intervention Program for Children With Congenital Heart Defects
|
N/A | |
| Enrolling by invitation |
NCT06122636 -
Efficacy of a Probiotic and Microbiological Analysis on Oral Complications Induced by Antineoplastic Therapies in Patients With HNC
|
N/A |