Clinical Trials Logo

Clinical Trial Summary

Since plaque control forms the basis for caries prevention, the type of toothpaste and its constituents becomes more important. Toothpaste containing fluoride are widely popular and fluorides have been historically reported to have effects against dental caries. However, the fluoride safe doses are still discussed ,because fluoride has toxicity and causing fluorosis. The aim of the current research is to find alternative agent that can be used without side effects.

Clinical Trial Description

Participants will be examined to ensure that they have met the smple entrey criteria,then the participants will be randomly assigned to four groups each one according to a group: 1. A group of children using low-fluoridated toothpaste (500ppm) 2. A group of children using fluoridated toothpaste (1450ppm) 3. A group of children using theobromine toothpaste (2%) 4. A group of children using low-fluoridated toothpaste (4%) The researcher will teach the participants how to brush using (tell-show-do)technique. - The brushing method that will be used is the fones technique. - Brushing duration must be 2minutes. - Frequency of brushing must be twice a day - The amount of toothpaste used is pea size. Mechanism of examination and follow up: A thorough scaling and plaque removal was conducted and the children were advised to brush their teeth using their regular toothpaste for a week before starting the research. Gingival will be evaluated with gingival index (loe and silness) ;

Study Design

Related Conditions & MeSH terms

NCT number NCT05187507
Study type Interventional
Source Damascus University
Status Completed
Phase N/A
Start date September 25, 2021
Completion date December 1, 2021

See also
  Status Clinical Trial Phase
Completed NCT04561960 - Efficacy of Miswak in Oral Hygiene Maintenance Phase 4
Completed NCT04025684 - Efficacy of Manual Toothbrushes in Removing Dental Plaque N/A
Completed NCT03394729 - Effect of a Propolis Tablet on the Saliva and the Amount of Adolescent Dental Plaque Microbes Phase 2/Phase 3
Completed NCT04485520 - Efficacy of the Extract of Carica Papaya as an Inhibitor of Streptococcus Mutans N/A
Completed NCT02552589 - Effect of Toothpaste on the Reduction of Plaque and Inflammation N/A
Completed NCT02884817 - Essential Oil+ELA, Plaque and Gingivitis Phase 4
Completed NCT02194023 - Clinical Effects of Two New Chlorhexidine Digluconate Formulations: 0.12% and 0.03%. Phase 2
Completed NCT01237782 - Efficacy of a Propolis-based Denture Cleanser N/A
Completed NCT00758394 - Clinical Study to Compare Dental Plaque Control Phase 3
Completed NCT00254345 - Effect of Provisional-Crown Surface Coating on Biofilm Formation Phase 1
Not yet recruiting NCT05038293 - Efficacy of Plaque Removal of a Novel Brushing Device N/A
Recruiting NCT05082103 - Effect of Enzymes on Dental Biofilm Accumulation in Healthy Individuals N/A
Completed NCT03311438 - Oral Health Intervention Program for Children With Congenital Heart Defects N/A
Completed NCT02856880 - A Study to Investigate the Antimicrobial Activity of 2 Test Toothpastes N/A
Active, not recruiting NCT02271815 - A Clinical and Imaging Study to Evaluate a Novel Dentifrice
Completed NCT01900353 - Vertical vs Horizontal Brushing: a Randomized Split-mouth Clinical Trial N/A
Completed NCT01580943 - Efficacy of Two Commercially Available Chlorhexidine Mouthrinses Non-alcohol Base Phase 1/Phase 2
Completed NCT01021007 - Clinical Research Study Efficacy of a Prototype Oral Rinse Phase 3
Not yet recruiting NCT05089214 - ONE-1 Oral graNd Est 1 N/A
Not yet recruiting NCT02911766 - Efficacy of Different Chlorhexidine Concentrations Phase 4