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Dental Plaque clinical trials

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NCT ID: NCT04881357 Completed - Periodontitis Clinical Trials

Antiplaque/Antigingivitis Effect of Lacer Oros Integral

LacerINT
Start date: September 4, 2021
Phase: N/A
Study type: Interventional

Background; A new mouth rinse formulation ("Lacer Oros Acción Integral", Lacer SA, Barcelona, Spain) has been recently proposed, including O-Cymen-5-ol, potassium nitrate, zinc chloride, dipotassium glycyrrhizate, sodium fluoride, panthenol and xylitol, within its ingredients. Thus, it may be relevant to test the efficacy of this new "Lacer Oros Acción Integral" mouth rinse formulation in a RCT. Primary Objective: The primary objective of this RCT will be to evaluate the antiplaque/antigingivitis effects of the test mouth rinse. Population: Consecutive subjects in supportive periodontal therapy (SPT) will be screened at the Post-Graduate Periodontal Clinic in the University Complutense, Madrid, and enrolled in the clinical trial if they are periodontitis patients, already enrolled in a SPT, for at least 6 months, systemically healthy, with moderate gingival inflammation and complains of dentin hypersensitivity. Study design: pilot, parallel, double-blind, randomized, placebo-controlled, 12-week, clinical trial Intervention: The experimental group will use three times daily a provided manual toothbrush with a sodium fluoride dentifrice, followed by the use of the test mouth rinse (Lacer Oros Acción Integral - new formula, Barcelona, Spain). The control group will use three times daily a provided manual toothbrush with a sodium fluoride dentifrice, followed by the use of the control mouth rinse (Lacer Oros Acción Integral - new formula, without active ingredients, Barcelona, Spain). Visits: Screening, baseline, 2 and 12 weeks. Outcomes: Periodontal clinical outcomes (plaque levels, gingival condition, probing pocket depth), Stainign, Microbiological outcomes (culture and qPCR). Patient reported outcomes, compliance, adverse effects.

NCT ID: NCT04853745 Completed - Dental Plaque Clinical Trials

The Effect of Air Polishing on the Tooth Surface

Start date: July 24, 2019
Phase:
Study type: Observational

The use of air-polishing device that operates by directing a fine slurry of pressurized air, water, and abrasive particles has become widespread in dentistry for polishing. The introduction of abrasive powders with different properties creates the need to evaluate the effects of these powders on dental hard tissues. This study was focused on the effect of sodium bicarbonate, glycine and erythritol air polishing on enamel and exposed root surface.

NCT ID: NCT04845633 Completed - Dental Plaque Clinical Trials

Effectiveness of Customized Handle Toothbrush

Start date: April 9, 2021
Phase: N/A
Study type: Interventional

People with special needs suffer from many difficulties, including mental, physical or motor, which increase the difficulty of obtaining good oral health. Therefore, some adjustments must be made to help these patients maintain oral health. The aim of the current research is to modify the traditional toothbrush grip by manufacturing a Customized Handle of every young child or people with special needs to improve oral health for those patients by relying on themselves with an effectively way.

NCT ID: NCT04830176 Completed - Plaque, Dental Clinical Trials

Role of Herbal Dentifrices in the Management of Plaque Induced Gingivitis

Start date: January 20, 2021
Phase: N/A
Study type: Interventional

The clinical cross over study involves the use of two herbal based dentifirices moringa and miswak and its efficacy in reducing plaque induced gingivitis. The patients selected are provided with details regarding the research format and consent taken.

NCT ID: NCT04794452 Completed - Plaque, Dental Clinical Trials

Dental Plaque Removal Evaluation and Comparison of Kid's Battery-Operated Toothbrush and Manual Toothbrush

Start date: November 23, 2020
Phase: N/A
Study type: Interventional

To evaluate and compare the plaque removal efficacy of a children's battery-powered toothbrush and a children's manual toothbrush following a single brushing.

NCT ID: NCT04794439 Completed - Plaque, Dental Clinical Trials

Plaque Removal Efficacy of Four Dentifrices Following a Single Brushing

Start date: November 16, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate and compare plaque removal efficacy of four dentifrices following a single timed tooth brushing. Prior to each evaluation visit of the four-way cross-over study, subjects will abstain from all oral hygiene for 24 hours. At each evaluation visit, subjects will be given a pre-brushing plaque evaluation, followed by a 1-minute supervised brushing and a post-brushing plaque evaluation.

NCT ID: NCT04788550 Recruiting - Clinical trials for Orthodontic Appliance Complication

The Effect of Different Remineralizing Agents on White Spot Lesions and Dental Plaque During Orthodontic Retention

Start date: March 17, 2021
Phase: N/A
Study type: Interventional

Dental caries is a decay process that breaks down the tooth. The earliest clinical signs of active dental caries is seen as 'white spot lesions' (WSLs). WSLs causes porosity below the tooth surface as a result of demineralization that gives the lesion a milky white appearance. Many WSLs persevere even a decade after orthodontic appliance removal and remain a cosmetic problem. After removal of fixed appliances, a considerable improvement of WSLs can be seen during the first 6-24 months, but the degree of improvement varies between individuals. Two common bacteria in dental plaque causes caries: Streptococcus mutans (SM) and Lactobacillus acidophilus (LA) in the plaque contributes to the initiation and progression of caries, respectively. A major strategy suggested to deal with existing WSL after debond is to facilitate remineralisation using remineralising agents that contain fluoride. This can be from daily use of fluoridated toothpastes or having additional dose of fluoride application. Certain agents also contain casein phosphopeptide-stabilize amorphous calcium phosphate (CPP-ACP) that is believed to have an antibacterial and buffering effect on plaque and interfere the growth and adherence of bacteria.

NCT ID: NCT04723732 Completed - Gingivitis Clinical Trials

Antiplaque, Antigingivitis and Anti-inflammatory Effects of Myrrh Mouthwash

Start date: August 15, 2017
Phase: N/A
Study type: Interventional

Myrrh-based mouthwash has the potential to be a suitable alternative to the gold standard chlorhexidine mouthwash for dental plaque and gingivitis reduction. To date, however, little research has been carried out to determine its true clinical significance on periodontal health. The purpose of this study is to evaluate and compare the efficacy of 1% myrrh mouthwash with commercially available 0.2% chlorhexidine mouthwash in terms of plaque and gingivitis reduction and inflammatory mediator (interleukin-1β) inhibition.

NCT ID: NCT04713566 Not yet recruiting - Plaque, Dental Clinical Trials

Comparative Clinical Effects of Salvadora Persica Oral Rinse And A Phenolic Commercial Mouth Wash On Human Oral Health

RCT
Start date: March 1, 2021
Phase: N/A
Study type: Interventional

ABSTRACT: OBJECTIVE: To compare the clinical effects of Salvadora persica (miswak) oral rinse and commercial Listerein mouth wash on oral health of socially deprived madrasa girls. METHODS: Girls aged 18-22 years living permanently in a madrasa of Multan city will be recruited. Sample size and trial duration will be determined using the American Dental Association guidelines. Participants will be randomized into two interventional groups; A and B and will be either provided with Salvadora persica oral rinse and commercial Listerein mouth wash respectively. Pre, mid and post-intervention examinations will be executed by a blind and calibrated examiner using Turesky Quigley Hein Plaque and Loe and Silness Gingival indices. Statistical analysis will include descriptive statistics and two sample independent t-tests. The p-value of <0.05 will be considered significant at 95 % confidence level. KEY WORDS: Dental plaque, Gingivitis, Miswak, Mouthwash

NCT ID: NCT04681885 Completed - Gingivitis Clinical Trials

Evaluation of Toothbrush Bristles in Plaque Reduction

Start date: June 30, 2021
Phase: N/A
Study type: Interventional

The purpose of this cross-over clinical research is to evaluate the cleaning efficacy of toothbrushes tufted with two types of tapered bristles and end rounded bristles in removal of interdental plaque with clinical measurement (Plaque Index) and objective measurement (digitally measured plaque area). This study will demonstrate the influence by a type of processing bristles on removal of interdental plaque and determine an agreement between the different evaluation methods. This is a randomized evaluator-masked crossover study with 10 subjects. Subjects will be randomly allocated to three test groups. Subjects will use the assigned toothbrush at baseline appointment and two times a day for a week. Plaque Index and plaque area will be assessed before/after one time use at baseline and Day 7. Subjects will be assigned to another toothbrush after one week wash-out period.