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Dental Plaque clinical trials

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NCT ID: NCT05853679 Completed - Dental Plaque Clinical Trials

Regular Antibacterial Photodynamic Therapy on Oral Hygiene in Elderly Residents

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

Around 40 people will participate in the study. The study participants will be recruited from service homes in the City of Helsinki. The subjects will be randomized into two groups. One of the groups will receive daily photodynamic Lumoral treatment for 2 months in a home care unit according to a separate instruction manual. At the beginning of the study, all subjects will receive an oral cleaning and will also be provided with electric toothbrushes. In addition, residents and care home personnel will be instructed on daily tooth cleaning. During the study, all participants will undergo clinical measurements and an assessment of the oral inflammatory load. The samples will be stored for later analysis. In addition, residents or care home personnel answer questions about oral self-care. These measurements and examinations will be carried out at the start of the study and two months after the start of the study. After the end of the study, participants will continue to be treated according to their usual care and individual care plan.

NCT ID: NCT05852145 Not yet recruiting - Dental Plaque Clinical Trials

Oral Changes With Caloric and no Caloric Sweeteners

Start date: October 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The objective of this clinical trial is to compare the effect that the intake of beverages without sweetwners, added with non-caloric sweeteners (stevioside) and caloric sweeteners (sucrose) on oral pH and dental biofilm microbiome in Mexican adolescents. Participants will drink on different occasions a beverage without sweetener, a beverage added with stevioside or a beverage added with sucrose. The researchers will compare the changes that each one causes in salivary pH, dental biofilm pH, dental biofilm bacterial proliferation and dental biofilm microbiome.

NCT ID: NCT05825742 Recruiting - Clinical trials for Orthodontic Appliance Complication

Regular Home Use of Dual-light Photodynamic Therapy on Oral Health in Adolescents Undergoing Fixed Orthodontic Treatment

Start date: September 5, 2023
Phase: N/A
Study type: Interventional

This study is designed to determine the efficacy of the Lumoral method on oral health in adolescents undergoing fixed orthodontic treatment. Improved supragingival plaque control can help to also sustain the subgingival plaque management in the long term. In addition, the device might have a photobiomodulation effect on periodontal tissues.

NCT ID: NCT05821712 Completed - Plaque Clinical Trials

A New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems

Start date: March 8, 2021
Phase: Phase 3
Study type: Interventional

This 6-month clinical study was designed to investigate clinical efficacy on plaque and gingivitis for the Meridol Base Mouthwash containing 0.2% zinc lactate, 0.17% amine fluoride and 0.0275% sodium fluoride as compared to a Negative Control Mouthwash containing 0.057% sodium fluoride after 3 and 6 months of product use.

NCT ID: NCT05805761 Not yet recruiting - Dental Plaque Clinical Trials

Antimicrobial Photodynamic Therapy With Erythrosine and Blue Light on Dental Biofilm Bacteria

Start date: August 20, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The objective of this study is to investigate the effect of Antimicrobial Photodynamic Therapy mediated by Erythrosine and blue LED in the reduction of bacteria in dental biofilm. This clinical trial will be carried out with 30 patients who have biofilm, but without the presence of periodontal pockets, and who are being treated at the Dental Clinic of Universidade Metropolitana de Santos. A split-mouth model will be used (n = 30), with group I control - conventional treatment and group II - conventional treatment and antimicrobial photodynamic therapy (aPDT). The bicarbonate jet will be used to remove dental biofilm in both groups. The treatment will be carried out in 1 session. aPDT will be performed before cleaning/prophylaxis, only in group II. Participants will rinse with the photosensitizer erythrosine (diluted to 1mM) for 1 min of pre-irradiation time, so that the drug can stain all the bacterial biofilm. Then, the D-2000 LED (DMC) will be applied, emitting at a wavelength of ʎ = 430-490 nm and 900-1100 mW/cm2. Irradiation will be performed until the biofilm of the cervical region is illuminated for 2 min per point. Each irradiation point will be approximately 0.4 cm2. The microbiological examination will be performed from samples of supragingival biofilm collected from the gingival sulcus. Two collections will be performed in each experimental site before irradiation, and immediately after the irradiation procedure (group II) or prophylaxis (groups I and II). Biofilm samples will be collected before and after exposure, respectively, and sent to the microbiological laboratory for colony counting. After this period, the CFU's will be counted and the data will be submitted to statistical analysis for comparison of pre and post-treatment results and between groups (conventional X aPDT).

NCT ID: NCT05793099 Completed - Child Clinical Trials

Effect of 5% Aqueous Propolis in Salivary and Dental Plaque pH in Children

Start date: December 16, 2022
Phase: N/A
Study type: Interventional

This study aims to investigate the changes in saliva and dental plaque pH after consuming sugar-free chewing gum containing 5% of aqueous propolis in children aged between 8-11 years. The studied sample will be divided into two groups: Group A (Control group) placebo chewing gum, and Group B (Experimental group) aqueous propolis chewing gum. All children will experience both types of chewing gum with an interval of 1 week between the two studied groups.

NCT ID: NCT05788692 Completed - Gingivitis Clinical Trials

Effectiveness of Toothbrushing Habits of Preschool Children, With or Without a Toothbrushing Assisting Application

Start date: February 15, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effectiveness of the use of a toothbrushing assisting mobile application in dental plaque removal and adherence to the toothbrushing routine, in preschool children (3-5 yrs old) when brushing with either manual or powered toothbrush. Objectives: To identify the effectiveness in dental plaque control in relation to the following parental characteristics: - Sociodemographic (area of residence, average income, education level) - Oral Health status - Oral Health Literacy - Parenting style - Parental oral hygiene practices

NCT ID: NCT05782348 Recruiting - Gingivitis Clinical Trials

Evaluating the Effectiveness of a Cognitive Behavioral Intervention (CBI)

Start date: February 6, 2023
Phase: N/A
Study type: Interventional

This is a Phase III, randomized, one-center, three arm parallel group, open label and single blind clinical study to evaluate the effectiveness of a cognitive behavioral intervention (CBI) adjunctive to a smart powered toothbrush on the oral health of adolescents.

NCT ID: NCT05779332 Completed - Dental Caries Clinical Trials

Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization

Start date: February 1, 2020
Phase:
Study type: Observational

Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL).

NCT ID: NCT05734456 Recruiting - Tooth Plaque Clinical Trials

Comparison Between Modified Bass and Horizontal Brushing Techniques

Start date: October 4, 2022
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to determine mean plaque scores to compare the effectiveness after using modified bass and horizontal brushing technique in undergraduate dental students. The main question[s] it aims to answer are: - Modified bass method is less effective than the horizontal brushing technique for plaque removal in undergraduate dental students - Modified bass method is more effective than the horizontal brushing technique for plaque in undergraduate dental students. Participants will check plaque scores with the help of probe and disclosing agents after applying both techniques in a separate quadrant on the same subject. Researchers will compare modified bass and a horizontal brushing technique to see which one is reliable and more effective.