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Dental Caries clinical trials

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NCT ID: NCT06372561 Recruiting - Clinical trials for Dental Caries in Children

Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study

Start date: May 20, 2023
Phase: N/A
Study type: Interventional

The process of dental caries is dynamic and can be either reversible or irreversible depending on the balance between protective and pathologic factors in the oral cavity. Untreated dental caries causes pulpal injury, inflammation, and necrosis. Melatonin plays an essential role in the regulation of bone growth. The actions that melatonin exerts on odontoblasts may be similar to its action on osteoblasts.

NCT ID: NCT06350578 Recruiting - Dental Caries Clinical Trials

A Randomized Clinical Trial Comparing Hall vs. Conventional Technique in Primary Molars.

Start date: December 6, 2023
Phase: N/A
Study type: Interventional

This study aims to assess the comparative effectiveness of the Hall technique (HT) and the conventional technique (CT) for placing Stainless Steel Crowns (SSCs) in primary molars with approximal caries.

NCT ID: NCT06308796 Recruiting - Clinical trials for Head and Neck Cancer

Prevention of Caries in Head and Neck Cancer Survivors Who Underwent Radiotherapy

RADIOCARIES
Start date: April 1, 2023
Phase: N/A
Study type: Interventional

One of the long-term side effects of head and neck radiotherapy (RT) is radiation-induced tooth decay. Hyposalivation, associated with radiation therapy, further increases caries susceptibility and caries progression, due to the lack of salivary protective effects and of tooth minerals useful for remineralization processes, especially calcium phosphate (CaP). Dental extractions that could be required in case of severe tooth decay expose the patient to the risk of osteoradionecrosis of the jaws (i.e. the necrosis of the bone tissue following a local trauma, including surgical trauma). This protocol aims at verifying the effectiveness of CaP mousse in the prevention of carious lesions, added to topical fluoride. A randomized controlled clinical trial will be performed comparing CaP + fluoride treatment versus no treatment in head and neck cancer patients, who received radiotherapy. The hypothesis is that CaP, which is lacking in the mouth of these patients due to hyposalivation, can combine with fluoride to promote remineralization, reducing the risk of carious lesions.

NCT ID: NCT06283108 Recruiting - Clinical trials for Dental Caries in Children

Gurney Journey: Virtual Reality Distraction

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to determine whether a software virtual reality (VR) program provided during transportation to anesthesia induction reduces anxiety before the procedure, and compliance in pediatric patients. This study aims to measure the anxiety of patients as they arrive before their procedure, when parting from their parents for transportation to the procedure room, and when anesthesia is provided. Compliance during anesthesia induction will also be monitored. Participants will be randomly placed into to one of two groups. Group 1 will receive standard care from a Certified Child Life Specialist prior to their surgery. Group 2 will receive standard care from a Certified Child Life Specialist and distraction with a novel virtual reality software program.

NCT ID: NCT06276959 Recruiting - Dental Caries Clinical Trials

The Effectiveness of iTero Element 5D NIRI System in Early Proximal Caries Detection in Permanent Teeth

Start date: January 1, 2023
Phase:
Study type: Observational

As a new emerging technology for the diagnosis of dental caries, near-infrared imaging requires further research and validation to determine its effectiveness. This study aims to compare near-infrared imaging with cone-beam computed tomography (CBCT) to validate the efficiency of near-infrared imaging in diagnosing proximal caries using large-scale clinical data through retrospective cross-sectional studies.

NCT ID: NCT06265116 Recruiting - Clinical trials for Dental Caries Class II

One-Step Universal Adhesives: A 3-year Clinical Trial in Class II Composite Restorations

Start date: January 23, 2024
Phase: N/A
Study type: Interventional

to evaluate and compare the clinical performance and periodontal responses of four commercially available one-step universal adhesives with different formulations in Class II composite restorations over a three-year period.

NCT ID: NCT06258798 Recruiting - Dental Caries Clinical Trials

The Use of Artificial Intelligence in the Dental X-rays Analysis

Start date: January 1, 2024
Phase:
Study type: Observational

This cross-sectional study aims to perform a population-based assessment of the incidence of decay, dental fillings, root canal fillings, endodontic lesions, implants, implant and dental abutment crowns, pontic crowns, and missing teeth, taking into account the location.

NCT ID: NCT06235489 Recruiting - Clinical trials for Dental Caries Class II

Evaluation of Clinical Success of Bulk Fil Composite Versus Highly Viscous Glass Ionomer in Primary Class II Molars

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

evaluate the clinical performance of EQUIA Forte ® ( a HVGIC) and Plafique® Bulk Flow composite resin when placed in class II cavities in primary molars.

NCT ID: NCT06231823 Recruiting - Caries Clinical Trials

Extraction of the Compromised First Permanent Molars

FPM
Start date: January 1, 2024
Phase: N/A
Study type: Interventional

Compromised first permanent molars (FPM), whether diagnosed with severe molar incisor hypomineralization (MIH), irreversible pulpities, or necrosis, require frequent re-treatment consequently entering the restorative cycle, which leads to their inevitable extraction and implant placement. Extraction of compromised first permanent molars in 8-10-year-old children allows the mesial migration of the second permanent molars during their eruption, thereby favoring spontaneous space closure as a permanent solution.

NCT ID: NCT06205459 Recruiting - Deep Caries Clinical Trials

Deep Marginal Acquisition With Thermacut Bur Vs. Functional Crown Lengthening in Deep Carious Lesions

Start date: February 2, 2024
Phase: N/A
Study type: Interventional

this clinical trial is conducted to compare between deep marginal acquistion by the means of thermacut bur Vs. functional crown lengthening in exposing deep subgingival interproximal cervical lesions