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Dental Caries clinical trials

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NCT ID: NCT06162182 Active, not recruiting - Caries,Dental Clinical Trials

Comparative Evaluation of an Electrical Impedance Device Versus Digital Radiography in Estimation of Remaining Dentin Thickness

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

The research question was that in patients with carious posterior permanent teeth, would the electrical impedance device be as valid as digital radiography in estimation of remaining dentin thickness? The proposed hypothesis was null.

NCT ID: NCT06155773 Active, not recruiting - Dental Caries Clinical Trials

Clinical Performance of Onlay Restorations After Cervical Margin Relocation (CMR)

Start date: August 24, 2021
Phase: N/A
Study type: Interventional

The current study intends to evaluate the effect of cervical margin relocation with different restorative materials on three-year clinical performance of indirect Computer-Aided-Design (CAD)/ Computer-Aided-Manufacture (CAM) onlay restorations. This study is designed to test the null hypothesis that the three-year clinical performance of onlay restorations is significantly affected by cervical margin relocation with different restorative materials.

NCT ID: NCT06129357 Active, not recruiting - Periodontitis Clinical Trials

Evaluation of Nutritional Habits, Oral Hygiene, Relationship Between Dental Caries and Periodontal Condition

Start date: February 2, 2023
Phase:
Study type: Observational

The purpose of this observational study is to identify the dental and periodontal health issues, oral hygiene practices, and potential relationships between them by assessing the variables that may have an impact on them.The main questions its aims to answer are: Is there a relationship between compliance with the Mediterranean diet and periodontal status? Is there a relationship between physical activity and periodontal status?

NCT ID: NCT06068244 Active, not recruiting - Clinical trials for Dental Caries in Children

3D-printed Crowns Versus Zirconia Crowns for Primary Molars

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

The aim of the present study is to compare between 3D-printed crowns and prefabricated zirconia crowns for restoring pulpally-treated primary molars regarding the following aspects: 1. In vivo: Evaluate the clinical outcome of 3D printed crowns in comparison to prefabricated zirconia crowns in pulpally-treated primary molars as well as parent satisfaction. 2. In vitro: Comparative analysis of fracture resistance and marginal gap of 3D printed crowns and prefabricated zirconia crowns

NCT ID: NCT05935813 Active, not recruiting - Caries,Dental Clinical Trials

Caries in Adolescents (Karies Hos Ungdom)

Start date: January 1, 2008
Phase:
Study type: Observational

In this study the objective is to establish in depth knowledge about adolescents' oral health characteristics, - practices and - needs. Further, we want to evaluate whether adolescents' caries status can be associated with existing socio-economic inequality, emotional health and lifestyle factors. The main question[s] it aims to answer are: 1. What is the caries status (i.e. prevalence, increment at different timepoints and characteristics) among adolescents in Trøndelag? - What is the caries prevalence in different age groups? - Is there any difference in caries prevalence linked to specific age groups, gender or urban versus rural areas? - Are approximal tooth surfaces especially prone to the development of new caries lesions? - Is the caries increment from 12 to 20 years a continuous process or are there high-risk periods within this timespan? - How is the prevalence of enamel caries? Is enamel caries more prevalent in younger age groups than in older age groups? 2. What are the patterns of recall intervals and non-attendance in different age groups, among adolescents in Trøndelag? - What are the attendance rates and prevalence of non-attendance at dental appointments in different age groups? - What is the recall interval between regular follow-up dental visits? - Are there any recall or attendance characteristics linked to age group, gender or urban versus rural areas? 3. What factors (i.e. oral health behaviours, socioeconomic-, lifestyle- and parental factors) are associated with caries among Norwegian adolescents? - How are the oral health behaviours (i.e. dietary- and oral hygiene habits, attendance to dental care) among adolescents, and are there any shared oral health behavioural challenges? - Is the caries prevalence linked to life challenges (mental illness, alcohol/drug use and chronic diseases)? - To what degree are oral health behaviours associated with caries among adolescents? - Is there any association between media screen time and oral health behaviours, and cariesstatus? - Is there any association between physical activity, sport participation and oral health behaviours, and caries status? - What are the associations between socioeconomic factors (study program, birth- and migration background, and parental income, education and employment) and oral health behaviours, and caries status? For research question 1 and 2, the sample will be adolescents aged 12-20 years living in Trøndelag county in the time period 2008-2020, (n≈115000, Statistics Norway, SSB). Data will be extracted from dental health records in the public dental service (Den offentlige tannhelsetjenesten, Trøndelag Fylkeskommune). The public dental service annually reports caries prevalence for 12- and 18-year-olds, Statistics Norway, SSB (Figure 1). However, the knowledge is modest about the caries development within the six years from 12 to 18 years of age. Further, the public dental service offers subsidised dental care to 19- and 20-year-olds. Extracting data from dental health records in the public dental service will give us the opportunity to explore the caries increment at multiple timepoints, and attendance rates at dental appointments throughout the teenage period from 12 to 20 years of age. For research question 3, the sample will be adolescents (n≈8000) and their parents that participated in the fourth survey of The Trøndelag Health Study (HUNT4) in 2017-2019. Self-reported questionnaire data will be linked to data from dental health records in the public dental service.

NCT ID: NCT05902975 Active, not recruiting - Clinical trials for Dental Caries in Children

Evaluation of the Antimicrobial Fiber Reinforced Composite Resin Space Maintainer Modified With Silver Nano Particles

Start date: May 21, 2022
Phase: N/A
Study type: Interventional

Fiber reinforced composite resin space maintainer

NCT ID: NCT05733923 Active, not recruiting - Dental Caries Clinical Trials

Evaluation of Chemo-mechanical Caries Removal Materials in Caries Removal

Start date: February 25, 2023
Phase: N/A
Study type: Interventional

• The evolution of conservative dentistry that adopts the preservation of tooth structure and affected dentin that can remineralize and save the pulp from exposure, in addition to pain and fear that companies' traditional caries removal methods had led to the development of chemomechanical caries removal materials (CMCR). The old generations of CMCR agents were NaOcl-based materials which have disadvantages such as odor taste, Unpleasant smell, high cost, Limited shelf life, and time consumption. • All of the reasons described led to a new generation of CMCR materials depending on Enzymes such as Papain. Brix3000 and Papacarie duo are Papain-based materials with promising effects in caries removal and fewer disadvantages. Selecti-solve is a dental gel whose active ingredient is papain enzyme, it removes dental caries without the need for anesthesia and is selective for the infected dentin layer only which avoids the unnecessary loss of dentin, enamel breaking, and pulp exposure. This study aims to evaluate the efficacy of Papain-based materials compared to old NAOcl-Based materials in reducing the disadvantages of CMCR agents.

NCT ID: NCT05670743 Active, not recruiting - Clinical trials for Dental Caries in Children

Pharmacokinetics of Advantage Arrest in Healthy Children 13-Months to 13-Years of Age

Start date: March 1, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this study is to further characterize basic pharmacokinetic (PK) parameters in healthy children to contribute to evidence for the safety of silver diamine fluoride (SDF; Advantage Arrest). Children with at least one active cavity will be treated and then have blood draws at random time points afterwards.

NCT ID: NCT05437432 Active, not recruiting - Dental Caries Clinical Trials

Esthetic Evaluation of Onlay Restorations Constructed From Vita Ambria Glass Ceramics

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

There is limited data available on VITA AMBRIA glass ceramic , so this study is conducted to investigate the esthetic parameters of this new glass press system.

NCT ID: NCT05418400 Active, not recruiting - Dental Caries Clinical Trials

Clinical Evaluation of Different Resin Composite Restorations

Start date: August 15, 2022
Phase: N/A
Study type: Interventional

Posterior resin composite is challenging esthetic restoration. Patients seek for durable, esthetic and functional restorations in molars. one of the major problems is polymerization shrinkage. Some materials were developed to overcome the polymerization shrinkage, among them bulk fill resin composite which have been developed to reduce the shrinkage stress during polymerization and offer much greater depth of cure. This is achieved by the addition of fillers such as barium aluminum silicate filler, ytterbium trifluoride and mixed oxides. Furthermore, a prepolymerized fillers have been added with silanes to reduce shrinkage stress. so, the objective of this trial is to clinical Evaluate and compare clinical performance of bulk fill VS incremental filling technique.