Efficacy of Ethyl Chloride Topical Anesthesia Application on the Pain

Status Recruiting

Clinical Trial Summary

The goal of this single-blinded randomized controlled trial is to compare pain perception during buccal infiltration using indirect EC spray and topical anesthesia and BC 20% topical gel, among seven to 10-year-old school children who attended Pediatric Dentistry Department at Dubai Dental Hospital (DDH), Mohammed Bin Rashid University (MBRU) in Dubai, the United Arab Emirates (UAE). The main question[s] it aims to answer are: • How effective is the indirect application of EC topical spray anesthesia on pain perception during intraoral buccal injection in children in comparsion to BC 20%? Researchers will compare efficacy of 20% Benzocaine (BC) gel and indirect application of Ethyl Chloride (EC) spray to see if reducing pain perception during local anesthesia infiltration.

Clinical Trial Description

Pre-local analgesia topical Benzocaine gel or Ethyl Chloride technique will be selected randomly and applied per the protocol. A single calibrated operator (A.A) using randomly selected sealed envelopes that have been previously divided equally according to sample size arms. The selected envelope is then opened by the operator, who applies either the EC or BC topical anesthesia technique based on the chosen envelop. Followed by maxillary local analgesia buccal infiltration for a single tooth by a calibrated operator (A.A). The child is then observed and assessed by the blinded primary investigator (N.A) (to the topical anesthesia technique) for pain perception during local anesthesia infiltration based on the Sound, Eye, Motor index used in this study. The child is then asked to rate the Visual Analog Scale and Facial Pain Scale. Heart rate of the patient will be recorded as per below protocol. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06011005
Study type	Interventional
Source	Mohammed Bin Rashid University of Medicine and Health Sciences
Contact	Nagah Abdelrahman
Phone	971551225599
Email	Nagah.abdelrahman@residents.mbru.ac.ae
Status	Recruiting
Phase	N/A
Start date	September 1, 2023
Completion date	December 31, 2023

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03663478` - Continuous TQL Block for Elective Cesarean Section	Phase 4
Completed	`NCT04513652` - A Study of the Safety and Anesthetic Effect of AG-920 Topical Ophthalmic Solution	Phase 3
Completed	`NCT05464862` - The Effect of PPB Using 10, 20 and 30 ml of Lidocaine, Study on Volunteers	Phase 4
Completed	`NCT04690647` - The Efficacy of Suprainguinal Fascia Iliaca Compartment Block for Analgesia After Elective Total Hip Replacement.	N/A
Completed	`NCT03245359` - Pain Management After TKA: Comparison of Short- and Long-term Nerve Blocks	N/A
Recruiting	`NCT06028126` - Superficial Parasternal Intercostal Plane Block in Cardiac Surgery Trial	N/A
Not yet recruiting	`NCT05815563` - Validation of Peripheral Perfusion Index in Predicting Successful Supraclavicular Brachial Plexus Block in Pediatrics
Completed	`NCT01418690` - Changes in Tissue Oxygenation Following Regional Anesthesia	N/A
Suspended	`NCT03291691` - Protective Nerve Stimulation in Regional Anesthesia
Not yet recruiting	`NCT03545516` - Wound Infiltration as Part of an Opioid Free Pain Management Pathway Following Cesarean Delivery	Phase 2
Not yet recruiting	`NCT05038007` - Pain After Lung Cancer Surgery - Comparing Traditional Versus Prolonged Release Nerve Blockades	Phase 2
Terminated	`NCT03672500` - Perineal Local Infiltration Study	N/A
Enrolling by invitation	`NCT06057090` - Do Therapy Dogs Improve Behavior and Reduce Anxiety in Pediatric Dental Patients?	N/A
Recruiting	`NCT05415865` - The Effect of Local Anesthetic Solution in the Bladder Prior to Botox Injections in the Bladder	Phase 3
Completed	`NCT04536311` - Surgical Stabilization of Rib Fractures While Awake or Under Appropriate Sedation by Paravertebral Block	N/A
Completed	`NCT03600454` - The Effect of Anesthesia on Perioperative Muscle Weakness and Neuro-endocrine Stress Response	N/A
Recruiting	`NCT03159338` - Platelet-rich Fibrin on Nerve Regeneration After Bilateral Sagittal Split Osteotomy	N/A
Completed	`NCT02966067` - A Split Mouth Trial to Compare Microneedles vs. Standard Needles in Dental Anaesthetic Delivery	N/A
Completed	`NCT03305666` - Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures	Phase 4
Recruiting	`NCT04960046` - A Comparison Between a PC and a CC Approach for the Placement of Infraclavicular Perineural Catheters in Hand Surgery	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Efficacy of Ethyl Chloride Topical Anesthesia Application on the Pain Perception During Intra-oral Injections in Children in Comparison to Benzocaine Gel.

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms