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Dental Caries in Children clinical trials

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NCT ID: NCT05607251 Not yet recruiting - Clinical trials for Dental Caries in Children

Salivary Alkaline Phosphatase as a Biomarker for Dental Caries in A Group of Egyptian Children With Different Growth Rates: A Descriptive Cross-Sectional Study

Start date: January 2023
Phase:
Study type: Observational

Aim of the study: 1. Assess the correlation between salivary alkaline phosphatase levels and dental caries. 2. Assess the effect of growth of children on the levels of salivary alkaline phosphatase enzyme. 3. Assess the effect of growth of children on caries experience and severity.

NCT ID: NCT05583682 Completed - Clinical trials for Dental Caries in Children

Clinical Performance of Resin-modified Glass Ionomer and Composite Restorations in Permanent Teeth

Start date: May 1, 2008
Phase: N/A
Study type: Interventional

The aim of this randomised controlled double-blinded, split mouth, single-center clinical trial was to evaluate the 18-month clinical performance of nano-filled resin-modified glass ionomer and sub-micron hybrid resin composite restorations in lower first permanent teeth of pediatric patients.

NCT ID: NCT05531435 Completed - Clinical trials for Dental Caries in Children

Local Anesthesia With Computerized Device for Restorative Procedures in Pediatric Patients

Start date: September 7, 2022
Phase: N/A
Study type: Interventional

The aim of the present study is to assess if there are differences on perceived pain during local anesthesia performed with SleeperOne device or with a traditional syringe in pediatric patients. Patients responding to the inclusion criteria will be asked to participate to the study. After signing the informed consent, they will undergo local anesthesia procedure on first or second primary molars for the subsequent performing of dental filling. The split-mouth design will randomly allocate first or second primary molar from one quadrant to SleeperOne procedure, while the contralateral one will be subdued to local anesthesia with traditional syringe. After the procedure, patients will be asked to assess the perceived pain with a Visual Analogue Scale from a range 0-10. VAS scales will be used to assess sensations of "size" (related to the two instruments), bitter and vomit.

NCT ID: NCT05529433 Not yet recruiting - Clinical trials for Dental Caries in Children

Pain Assessment During Chemo-Mechanical and Smart Burs Caries Removal Versus Atraumatic Restorative Treatment in Carious Primary Molars

Start date: September 2022
Phase: N/A
Study type: Interventional

The aim of the clinical trial is to assess pain during Atraumatic Restorative Treatment (ART), Smart Burs and Chemo-mechanical Caries Removal (CMCR) in primary molars.

NCT ID: NCT05512156 Recruiting - Clinical trials for Dental Caries in Children

Toothbrushing Program in Saudi Arabia "TOPS"

Start date: September 18, 2022
Phase: N/A
Study type: Interventional

Project summary Introduction: Dental caries is a major oral health problem worldwide. In children, dental caries is especially critical; it causes pain, infection and impacts on quality of life and it can potentially impact children's growth, nutrition, and educational attainment. Children in Saudi Arabia have among the highest caries levels in the world. The percentage of the children aged 6 and 12 years who suffer from tooth decay reached 96% and 93.7% respectively,2022. There are several interventions known to prevent tooth decay, such as water fluoridation and toothbrushing with fluoride toothpaste. A water fluoridation programme has already been introduced in parts of Saudi Arabia. The standard specification of tap water and bottled water in the Kingdom of 1.5 parts per million ,2007. Studies suggest that a programme of daily supervised toothbrushing in early year / education settings is potentially effective at reducing caries in the child population complementary to water fluoridation, although there is limited trial evidence. Aim: The aim of this project is to conduct a trial to assess the effectiveness of a supervised toothbrushing programme in kindergartens in Riyadh, Saudi Arabia . Methods: A cluster randomized controlled trial study will be undertaken in which the effectiveness of the daily supervised toothbrushing programme intervention running for two academic years will be randomly allocated to a sample of kindergartens in Riyadh and compared against treatment as usual which will be an annual oral health awareness visit in the control group of kindergartens over and above community water fluoridation. Effectiveness will be measured and delivered in terms of preventing dental caries in children when compared with children in the treatment as usual control group receiving the same level of community water fluoridation, but not the toothbrushing program intervention. All children in all kindergartens (both intervention and control groups) will have a dental examination (via trained and calibrated dental teams recording dental caries levels via dmft index) at baseline before intervention commences and at 2 years. In addition, questionnaires on behaviours and quality of life. In addition, process monitoring, and cost analysis surveys will be distributed. Research Questions: - Can such a supervised toothbrushing programme in kindergartens be effective at reducing the development of dental caries by 6 years of age? - Can a supervised toothbrushing programme in kindergartens in Saudi Arabia be established and implemented?

NCT ID: NCT05475145 Completed - Clinical trials for Dental Caries in Children

Sealing of Occlusal Dentin Caries in Primary Molars.

SealCar
Start date: February 2, 2015
Phase: N/A
Study type: Interventional

BACKGROUND A simple method for arresting dentin caries with a tight seal of the cavity would exclude the need for injection and excavation, reduce the risk for dental fear and possibly postpone or eliminate the need for further treatment. AIM The aim is to evaluate success-rate and children's subjective experience of resin-based sealing (RBS) and resin-modified glass ionomer cement (GIC) for treatment of occlusal dentin caries in primary molars. DESIGN Children aged 2-9 years will be recruited to undergo RBS- or GIC-treatment treatment for occlusal dentin caries in primary molars. A parent will answer the Short Form of Children's Fear Survey (CFSS-DS; parental version). No excavation but etching with 38% phosphoric acid will precede RBS. Topical and local anaesthesia and excavation with high speed bur will precede GIC. Time for treatment will be estimated. The children will rank their experience of each treatment on a 7-grade face scale. The dentist will evaluate the child's experience, cooperation and the overall experience of the treatment on a four-grade scale. The treatment will be evaluated as "without remark" or "defective" after 3, 6, 12, 24 and 36 months. For statistical analysis the Chi-2-test, Wilcoxon-Signed-Rank-test and Paired t-test will be used.

NCT ID: NCT05432258 Completed - Clinical trials for Dental Caries in Children

Nano-Hybrid vs Bulk-Fill Resin Composites

Start date: June 15, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to compare the 2-year clinical performance of bulk-fill composites, which can be applied as a single layer, and the nano-hybrid filled composite resins, which are frequently used in clinical routine, in children in a split-mouth design. This study was conducted on 89 patients aged 6-12 years who had caries on bilateral mandibular first molars. Our study has a randomized, cross-controlled, and double-blind design. In split-mouth design, restorations of mandibular permanent molars completed with nano-hybrid ORMOCER based bulk-fill filling material Admira Fusion x-tra (Voco GmbH, Cuxhaven, Germany) and nano-hybrid composite Grandio (Voco , Cuxhaven, Germany). Futurabond U single dose (Voco, Cuxhaven, Germany) universal adhesive was used for all restorations, in the selective enamel etching mode. The clinical success of the restorations will be evaluated at 6, 12 and 24-month controls. Evaluations has been made by two physicians other than the one who did the restoration, who do not know which restorative material was applied to which tooth.

NCT ID: NCT05395065 Completed - Clinical trials for Dental Caries in Children

Silver Diamine Fluoride Gel: Case Series

KiruPoderoso
Start date: July 11, 2022
Phase:
Study type: Observational

A clinical case series to determine the clinical response of dental caries lesions in primary teeth where 38% silver diamine fluoride gel is applied and cover with 2.5% sodium fluoride varnish. Additionally, to assess parent satisfaction with treatment with 38% silver diamine fluoride.

NCT ID: NCT05250609 Completed - Clinical trials for Dental Caries in Children

Clinical and Radiographic Evaluation of Resin Endocrown as Long Term Interim Restoration Versus Stainless Steel Crown for Endodontically Treated First Permanent Molar in Children: Randomized Controlled Pilot Study.

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

management of endodontically treated first permanent molar with deep dental caries is one of the challenging procedure that the operator face. Using resin endocrown or stainless steel crown restoration to make comparison which one is more successful in children.

NCT ID: NCT05221749 Terminated - Clinical trials for Microbial Colonization

The Antibacterial Effect of Nanosilver Fluoride on Primary Teeth

Start date: March 15, 2022
Phase: Phase 3
Study type: Interventional

To assess the antibacterial effect of Nanosilver Fluoride (NSF) in relation to caries activity in dentin caries lesions of primary teeth in comparison to Silver Diamine Fluoride (SDF).