Ventriculomegaly and Gait Disturbance in the Senior Population in the Region of Västerbotten

Dementia Clinical Trial

— VESPR  

Official title:

Gait and Balance Impairment, Dementia and Wide Brain Ventricles in the Ages 65-84 Years

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05204745
• Other study ID #: 2017/335-31
• Status: Completed
• Start date: February 14, 2018
• Est. completion date: December 22, 2021

Study information

• Verified date: January 2022
• Source: Umeå University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Idiopathic normal pressure hydrocephalus (INPH) is a treatable disease of the elderly, typically causing gait impariment, dementia and urinary incontinence. The objective of this study is to make an epidemiological survey of INPH in Umeå, Sweden. Subjects with self-perceived gait impairments will be identified through a questionnaire. They will go through clinical examinations and have an MRI of the brain. A control population will also be investigated to enable comparisons between the populations. The main hypothesis is that the prevalence of INPH in the population is higher than what is previoulsy known.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 6500
• Est. completion date: December 22, 2021
• Est. primary completion date: December 22, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 65 Years to 84 Years

Eligibility

Inclusion Criteria:

• Living in Umeå, Sweden.

Exclusion Criteria:

• Age <65 or >84 years when the questionnaire was sent out.
• Death at the time for the clinical evaluation.

Related Conditions & MeSH terms

• Brain Diseases
• Central Nervous System Diseases
• Dementia
• Gait Disorders, Neurologic
• Hydrocephalus
• Hydrocephalus, Normal Pressure
• Idiopathic Normal Pressure Hydrocephalus (INPH)
• Nervous System Diseases

Locations

Country	Name	City	State
Sweden	Norrlands Universitetssjukhus	Umeå	Västerbotten

Sponsors (2)

Lead Sponsor	Collaborator
Umeå University	Region Västerbotten

Country where clinical trial is conducted

Sweden, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of participants with Idiopathic Normal Pressure Hydrocephalus	Diagnosis of INPH based on clinical evaluation and MRI.	Through study completion, an average of approximately 1 month.