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Clinical Trial Summary

To study the effects of transcranial direct current stimulation on executive function in people with mild to moderate dementia


Clinical Trial Description

Extensive research had shown executive dysfunction in people with dementia (PWD) is associated with functional abnormalities in prefrontal regions such as the right inferior frontal gyrus (Right IFG) or the left dorsal lateral pre-frontal cortex (Left DLPFC) . Clinical studies suggest that tDCS may be a useful therapeutic tool. Post-tDCS improvements have also been shown in visuo-motor coordination of healthy controls and performance in working memory. The aim of this study is to investigate the effect of tDCS stimulation over left DLPFC or right IFG on attention, inhibition and working memory and their neural correlates in people with dementia (PWD) and healthy controls (HC).This study is planned as a double-blinded, randomized case-control interventional study with a duration of 30 months. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03753191
Study type Interventional
Source The Hong Kong Polytechnic University
Contact Frank LAI, PhD
Phone 2766 6749
Email frank.hy.lai@polyu.edu.hk
Status Recruiting
Phase N/A
Start date June 1, 2019
Completion date October 20, 2021

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